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The Measurement of Indirect Costs in the Health Economics Evaluation Literature: A Review

Published online by Cambridge University Press:  10 March 2009

Philip Jacobs  and
Konrad Fassbender
Philip Jacobs
Affiliation:
University of Alberta and Institute of PharmacoEconomics
Konrad Fassbender
Affiliation:
University of Alberta and Institute of PharmacoEconomics
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Abstract

In this paper we develop a framework to categorize the concepts used to estimate indirect costs in economic evaluation. We apply this framework in a literature review of economic evaluation studies. We searched all English language literature from 1994–1996. Following the application of a search algorithm, which yielded 25 articles, we abstracted information from these articles to determine the methods used to identify the relative contribution of indirect costs to the cost-effectiveness ratio, the time horizon selected by the authors, the identification of those activities that were foregone, the time given up by these activities, and the valuation placed on this time. These methods were then assessed. Indirect costs, as they have been measured, significantly influence efficiency ratios. A wide variation exists among studies in how they incorporate each of the components of indirect costs. All of the four components that were identified will affect the measurement of indirect cost. Future guidelines in this area should address the entire measurement process.

Keywords

CostCost analysisIndirect CostsEconomic Evaluation
Type
Research Note
Information
International Journal of Technology Assessment in Health Care , Volume 14 , Issue 4 , Fall 1998 , pp. 799 - 808
Copyright
Copyright © Cambridge University Press 1998

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References

REFERENCES

1.Barrett, B. J., Parfrey, P. S., Foley, R. N., & Detsky, A. S.An economic analysis of strategies for the use of contrast media for diagnostic cardiac catheterization. Medical Decision Making, 1994, 14, 325–35.Google Scholar
2.Berggren, U., Zethraeus, N., Arvidsson, D., Haglund, U., & Jonsson, B.A cost-minimization analysis of laparoscopic cholecystectomy versus open cholecystectomy. American Journal of Surgery, 1996, 172, 305–10.Google Scholar
3.Berman, S., Roark, R., & Luckey, D.Theoretical cost effectiveness of management options for children with persisting middle ear effusions. Pediatrics, 1994, 93, 353–63.Google Scholar
4.Bostman, O. M.Metallic or absorbable fracture fixation devices. A cost minimization analysis. Clinical Orthopaedics and Related Research, 1996, 329, 233–39.Google Scholar
5.Brouwer, W. B., Koopmanschap, M. A., & Rutten, F. F.Productivity costs on cost-effectiveness analysis: Numerator or denominator—A further discussion. Health Economics, 1997, 6, 511–14.Google Scholar
6.Canadian Coordinating Office for Health Technology Assessment. A guidance document for the costing process, version 1.0. Ottawa: Canadian Coordinating Office for Health Technology Assessment, 1996.Google Scholar
7.Canadian Coordinating Office for Health Technology Assessment. Guidelines for economic evaluation of Pharmaceuticals: Canada, 2nd ed.Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA), 1997.Google Scholar
8.Commonwealth Department of Human Services and Health, Australia. Australian guidelines. Canberra: Australian Government Publishing Service, 1995.Google Scholar
9.Cook, J., Richardson, J., & Street, A.A cost utility analysis of treatment options for gallstone disease: Methodological issues and results. Health Economics, 1994, 3, 157–68.CrossRefGoogle ScholarPubMed
10.Drummond, M. F., Torrance, G., & Stoddart, G.Methods for the economic evaluation of health care programmes. New York: Oxford University Press, 1987.Google Scholar
11.Fox-Rushby, J. A., & Foord, F.Costs, effects and cost-effectiveness analysis of a mobile maternal health care service in West Kiang, The Gambia. Health Policy, 1996, 35, 123–43.Google Scholar
12.Glied, S.Estimating the indirect cost of illness: An assessment of the foregone earnings approach. American Journal of Public Health, 1996, 86, 1723–28.CrossRefGoogle Scholar
13.Gold, M. R., Siegel, J. E., Russel, L. B., et al. Cost effectiveness in health and medicine. New York: Oxford University Press, 1996.Google Scholar
14.Goossens, M. E., Rutten-van, M. M. P., Leidl, R. M., et al. Cognitive-educational treatment of fibromyalgia: A randomized clinical trial, II: Economic evaluation. Journal of Rheumatology, 1996, 23,1246–54.Google ScholarPubMed
15.Gustafsson, O., Carlsson, P., Norming, U., Nyman, C. R., & Svensson, H.Cost-effectiveness analysis in early detection of prostate cancer: An evaluation of six screening strategies in a randomly selected population of 2,400 men. Prostate, 1995, 26, 299–309.Google Scholar
16.Jerrell, J. M., Hu, T. W., & Ridgely, M. S.Cost-effectiveness of substance disorder interventions for people with severe mental illness. Journal of Mental Health Administration, 1994, 3, 283–97.Google Scholar
17.Johannesson, M.Avoiding double-counting in pharmacoeconomic studies. Pharmacoeconomics, 1997, 11, 385–88.Google Scholar
18.Jordan, J. E., Marks, M. P., Lane, B., & Steinberg, G. K.Cost-effectiveness of endovascular therapy in the surgical management of cerebral arteriovenous malformations. AJNR: American Journal of Neuroradiology, 1996, 17, 247–54.Google ScholarPubMed
19.Koopmanschap, M. A., & Rutten, F. F.Indirect costs in economic studies: Confronting the confusion. Pharmacoeconomics, 1993, 4, 446–54.CrossRefGoogle ScholarPubMed
20.Koopmanschap, M. A., & Rutten, F. F.A practical guide for calculating indirect costs of disease. Pharmacoeconomics, 1996, 10, 460–66.Google Scholar
21.Koopmanschap, M. A., & van Ineveld, B. M.Towards a new approach for estimating indirect costs of disease. Social Science and Medicine, 1992, 34, 1005–10.Google Scholar
22.Koopmanschap, M. A., Rutten, F. F., van Ineveld, B. M., & van Roijen, L.The friction cost method for measuring indirect costs of disease. Journal of Health Economics, 1995, 14, 171–89.Google Scholar
23.Lieu, T. A., Cochi, S. L., Black, S. B., et al. Cost-effectiveness of a routine varicella vaccination program for U.S. children. JAMA, 1994, 271, 375–81.Google Scholar
24.Lindholm, L., Rosen, M., Weinehall, L., & Asplund, K.Cost effectiveness and equity of a community based cardiovascular disease prevention programme in Norsjo, Sweden. Journal of Epidemiology and Community Health, 1996, 50, 190–95.Google Scholar
25.Mansergh, G., Haddix, A. C., Steketee, R. W., et al. Cost-effectiveness of short-course zidovudine to prevent perinatal HIV type 1 infection in a sub-Saharan African developing country setting. JAMA, 1996, 276, 139–45.Google Scholar
26.Margolis, H. S., Coleman, P. J., Brown, R. E., et al. Prevention of hepatitis B virus transmission by immunization. An economic analysis of current recommendations. JAMA, 1995, 274, 1201–08.Google Scholar
27.Miller, M. A., Sutter, R. W., Strebel, P. M., & Hadler, S. C.Cost-effectiveness of incorporating inactivated poliovirus vaccine into the routine childhood immunization schedule. JAMA, 1996, 276, 967–71.CrossRefGoogle ScholarPubMed
28.Nordstrom, D. C., Konttinen, Y. T., Solovieva, S., Friman, C., & Santavirta, S.In- and out-patient rehabilitation in rheumatoid arthritis. A controlled, open, longitudinal, cost-effectiveness study. Scandinavian Journal of Rheumatology, 1996, 25, 200–06.Google Scholar
29.Norum, J., Angelsen, V., Wist, E., & Olsen, J.A.Treatment costs in Hodgkin's disease: A cost-utility analysis. European Journal of Cancer, 1996, 32A, 1510–17.Google Scholar
30.Nuijten, M. J., Hardens, M., & Souetre, E.A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression. Pharmacoeconomics, 1995, 2, 159–68.Google Scholar
31.Olsen, J. A.Production gains: Should they count in health care evaluations? Scottish Journal of Political Economy, 1994, 41, 69–84.Google Scholar
32.Osmond, M. H., Klassen, T. P., & Quinn, J. V.Economic comparison of a tissue adhesive and suturing in the repair of pediatric facial lacerations. Journal of Pediatrics, 1995, 126, 892–95.Google Scholar
33.Pelc, A., Portier, H., Gehanno, P., Fiessinger, S., & Ichou, F.Cost saving of 5-day therapy with cefpodoxime proxetil versus standard 10-day beta-lactam therapy for recurrent pharyngotonsillitis in adults. A prospective general practice study. Pharmacoeconomics, 1996, 3, 239–50.Google Scholar
34.Posnett, J., & Jan, S.Indirect cost in economic evaluation: The opportunity cost of unpaid inputs. Health Economics, 1996, 5, 13–23.Google Scholar
35.Shaw, W. D.Searching for the opportunity cost of an individual’s time. Land Economics, 1992, 68, 107–15.Google Scholar
36.Siegel, J. E., Torrance, G. W., Russell, L. B., et al. Guidelines for pharmacoeconomic studies. Recommendations from the Panel on Cost Effectiveness in Health and Medicine. Pharmacoeconomics, 1997, 11, 159–68.Google Scholar
37.Smith, J. C., Haddix, A. C., Teutsch, S. M., & Glass, R. I.Cost-effectiveness analysis of a rotavirus immunization program for the United States. Pediatrics, 1995, 96, 609–15.Google Scholar
38.Smith, P. S., Teutsch, S. M., Shaffer, P. A., Rolka, H., & Evatt, B.Episodic versus prophylactic infusions for hemophilia A: A cost-effectiveness analysis. Journal of Pediatrics, 1996, 129, 424–31.Google Scholar
39.Stevenson, R. C., McCabe, C. J., & Findlay, A. M.An economic evaluation of a clinical trial to compare automated percutaneous lumbar discectomy with microdiscectomy in the treatment of contained lumbar disc herniation. Spine, 1995, 20, 739–42.Google Scholar
40.U.S. Department of Health and Human Services. A practical guide to prevention effectiveness: decision and economic analysis. Atlanta: U.S. Department of Health and Human Services, 1997.Google Scholar
41.Van Damme, P., Tormans, G., Beutels, P., & Van Doorslaer, E.Hepatitis B prevention in Europe: A preliminary economic evaluation. Vaccine, 1995, 13, S54–57.Google Scholar
42.Watcha, M. F., & Smith, I.Cost-effectiveness analysis of antiemetic therapy for ambulatory surgery. Journal of Clinical Anesthesia, 1994, 6, 370–77.Google Scholar
43.Weinstein, M. C., Siegel, J. A., Garber, A. M., et al. Productivity costs, time costs, and health-related quality of life: A response to the Erasmus group. Health Economics, 1997, 6, 505–10.3.0.CO;2-I>CrossRefGoogle Scholar