Last year in the summer issue of this journal, Khandker et al. (3) published the results of an interesting modeling study following the cost-effectiveness of various strategies for detecting cases of colon cancer. In addition to the baseline alternative, the authors investigated eight different screening strategies and calculated the incremental cost-effectiveness of these eight strategies. Table 1 contains the results of their study in terms of cost and effectiveness as well as incremental cost-effectiveness (see Table 3, Khandler et al.).