High-Frequency Oscillatory Ventilation
Published online by Cambridge University Press: 10 March 2009
Extract
The improved survival rate of premature infants with respiratory failure is attributable to advances in mechanical ventilation, although an adverse consequence has been an increased incidence of bronchopulmonary dysplasia (BPD) (1;32). Positive pressure ventilation with its attendant “barotrauma” is suspected in the causation of BPD. While many attempts to alter respirator variables, such as pressure and time components, have produced optimal patterns for gas exchange, evidence is lacking to support any one pattern that minimizes the incidence of chronic lung injury. The high incidence of BPD has promoted a search for alternative methods of ventilation that might reduce lung injury through a reduction in peak pressure applied to the lung. Additional motivation has come from the need for oxygenation when mechanical ventilation has failed or pulmonary interstitial emphysema has developed. Less compelling reasons have come from the desire to avoid high swings in thoracic pressure that might adversely affect cardiac output, venous return, and cerebral blood flow.
- Type
- Neonatal Disorders of Respiration
- Information
- International Journal of Technology Assessment in Health Care , Volume 7 , Supplement S1 , January 1991 , pp. 41 - 46
- Copyright
- Copyright © Cambridge University Press 1991
References
REFERENCES
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