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The Desired Field-Performance Characteristics of New Improved Vaccines for the Developing World

Published online by Cambridge University Press:  14 October 2009

Ciro A. de Quadros ,
Peter Carrasco  and
Jean-Marc Olivé
Ciro A. de Quadros
Affiliation:
Pan American Health Organization
Peter Carrasco
Affiliation:
Pan American Health Organization
Jean-Marc Olivé
Affiliation:
Pan American Health Organization
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Abstract

Although the vaccination initiatives undertaken during the past decade are the cornerstones for protecting the world's children and helping to ensure their survival and development, the vaccines currently being employed may become obstacles for further disease reduction or eradication. Their characteristics complicate or increase the burden on health care infrastructures to maintain or expand vaccine delivery systems. This paper examines an experience with the vaccine technologies that currently are being used by immunization programs in developing countries, illustrating the field problems and obstacles associated with their use. It discusses the advantages and benefits that would accrue if new or improved, heat-stable, multi-antigen vaccines that require only one or two, preferably oral, doses were to become available.

Type
Research Article
Information
International Journal of Technology Assessment in Health Care , Volume 10 , Issue 1 , Winter 1994 , pp. 65 - 70
Copyright
Copyright © Cambridge University Press 1994

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References

REFERENCES

1.Carrasco, P., et al. Poliomyelitis epidemic in indigenous communities of northwestern Peru. In preparation, 1993.Google Scholar
2. Clinical efficacy of trivalent oral polio vaccine tested. EPI Newsletter. 1985, 7 (1).Google Scholar
3.Fenner, F., Henderson, D. A., Arita, I., et al. Smallpox and its eradication. Geneva, Switzerland: World Health Organization, 1988.Google Scholar
4. Missed opportunities in the Americas: Diagnosis and intervention. EPI Newsletter, 1991, 13 (3).Google Scholar
5.Pan American Health Organization. Reports on cold chain surveys in nine countries of the Americas. Washington, DC, 1989–1992.Google Scholar
6.de Quadros, C. A., Andrus, J. K., Olive, J. M., et al. Eradication of poliomyelitis: Progress in the Americas. Pediatric Infectious Diseases Journal. 1991, 10, 222–29.CrossRefGoogle ScholarPubMed
7.de Quadros, C. A., Andrus, J. K., Olive, J. M., et al. Polio eradication from the Western Hemisphere. Annual Review of Public Health, 1992, 13, 239–52.CrossRefGoogle ScholarPubMed
8.Strode, G. K., et al. Yellow fever. New York: McGraw-Hill Book Co., 1951.Google Scholar
9.World Health Organization. Monitoring adverse effects following immunization in the Expanded Programme on Immunization. Geneva, Switzerland: World Health Organization, 1991.Google Scholar
10.Wright, P., Kim-Farley, R. J., de Quadros, C. A., et al. Strategies for the global eradication of poliomyelitis by the year 2000. New England Journal of Medicine, 1991, 325, 1774–79.CrossRefGoogle ScholarPubMed