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Data validation in an economic evaluation of surgery for colon cancer

Published online by Cambridge University Press:  26 April 2005

Martin Janson ,
Per Carlsson ,
Eva Haglind  and
Bo Anderberg
Martin Janson
Affiliation:
Karolinska Institutet and University Hospital at Huddinge
Per Carlsson
Affiliation:
Linköping University
Eva Haglind
Affiliation:
Göteborg University and Sahlgrenska University Hospital
Bo Anderberg
Affiliation:
Karolinska Institutet and University Hospital at Huddinge
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Abstract

Objectives: This study aimed to validate the accuracy of data retrieved in a prospective multicenter trial, the purpose of which was an economic evaluation of two techniques of surgery for colon cancer.

Methods: Within the Swedish contribution of the COLOR trial (Colon Cancer Open or Laparoscopic Resection), an economic evaluation of open versus laparoscopic surgical techniques was conducted. Data were collected by case record forms (CRF), patient diaries, and telephone surveys every 2 weeks. The study period was 12 weeks, and the perspective was societal. Data from the first consecutive forty patients to complete the health economic study protocol were validated. Retrieved data were compared with data from medical records and data from local social security offices for agreement.

Results: Statistically significant differences were found for duration of anesthesia, length of surgery, number of outpatient consultations by doctors and district nurses, complication rate, and the use of central venous lines. No significant differences were observed concerning length of hospital stay, disposable instruments cost, and time off work, all of which heavily influence total costs.

Conclusions: The present method of data collection regarding resources used in this setting seems to produce accurate data for economic evaluation; however, relative to complication rates, the method did not retrieve accurate data.

Keywords

(MeSH) SurgeryRandomized controlled trialsData collectionCosts and cost analysisAccuracy
Type
RESEARCH REPORTS
Information
International Journal of Technology Assessment in Health Care , Volume 21 , Issue 2 , April 2005 , pp. 246 - 252
Copyright
© 2005 Cambridge University Press

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References

COLOR Study Group. 2000 COLOR: A randomized clinical trial comparing laparoscopic and open resection for colon cancer. Dig Surg. 17: 617– 622.
Bellon JA, Lardelli P, Luna JD, et al. 2000 Validity of self reported utilisation of primary health care services in an urban population in Spain. J Epidemiol Community Health. 54: 544– 551.Google Scholar
Berman IR. 1996 Laparoscopic resection for colon cancer: Cause for pause. Important Adv Oncol. 231– 243.Google Scholar
Clark RE, Ricketts SK, McHugo GJ. 1996 Measuring hospital use without claims: A comparison of patient and provider reports. Health Serv Res. 31: 153– 169.Google Scholar
Delaney CP, Kiran RP, Senagore AJ, et al. 2003 Case-matched comparison of clinical and financial outcome after laparoscopic or open colorectal surgery. Ann Surg. 238: 67– 72.Google Scholar
Dixon S, Deverill M, Gannon M, et al. 1999 Improving the validity of economic evaluations alongside controlled trials. J Health Serv Res Policy. 4: 161– 163.Google Scholar
Drummond MF, Davies L. 1991 Economic analysis alongside clinical trials. Revisiting the methodological issues. Int J Technol Assess Health Care. 7: 561– 573.Google Scholar
Drummond MF, Jefferson TO. 1996 Guidelines for authors and peer reviewers of economic submissions to the BMJ. The BMJ Economic Evaluation Working Party. BMJ. 313: 275– 283.Google Scholar
Drummond MF, O'Brien B, Stoddart GL. 1997. Methods for the economic evaluation of health care programmes. Oxford: Oxford University Press
Evans C, Crawford B. 1999 Patient self-reports in pharmacoeconomic studies. Their use and impact on study validity. Pharmacoeconomics. 15: 241– 256.Google Scholar
Evans CJ, Crawford B. 2000 Data collection methods in prospective economic evaluations: How accurate are the results? Value Health. 3: 277– 286.Google Scholar
Falk PM, Beart RW, Wexner SD, et al. 1993 Laparoscopic colectomy: A critical appraisal. Dis Colon Rectum. 36: 28– 34.Google Scholar
Fleiss JL. 1981. Statistical methods for rates and proportions. New York: Wiley
Freemantle N, Drummond M. 1997 Should clinical trials with concurrent economic analyses be blinded? JAMA. 277: 63– 64.Google Scholar
Gold RM, Siegel JE, Russel LB, et al. 1996. Cost effectiveness in health and medicine. Oxford: Oxford University Press;
Hazebroek EJ. 2002 COLOR: A randomized clinical trial comparing laparoscopic and open resection for colon cancer. Surg Endosc. 16: 949– 953.Google Scholar
Hoffman GC, Baker JW, Doxey JB, et al. 1996 Minimally invasive surgery for colorectal cancer. Initial follow-up. Ann Surg. 223: 790– 796, discussion 796-798.Google Scholar
Janson M, Björholt I, Carlsson P, et al. 2004 Randomized clinical trial of the costs of open and laparoscopic surgery for colon cancer. Br J Surg. 91: 409– 417.Google Scholar
Johnston K, Buxton MJ, Jones DR, et al. 1999 Assessing the costs of healthcare technologies in clinical trials. Health Technol Assess. 3: 1– 76.Google Scholar
Jönsson B, Zethraeus N. 1995. Costs and benefits of laparoscopic surgery. Stockholm: Centre for Health Economics, Stockholm School of Economics
Jönsson B, Zethraeus N. 2000 Costs and benefits of laparoscopic surgery-a review of the literature. Eur J Surg. 585 (Suppl): 48– 56.Google Scholar
Katz PP, Showstack JA, Lake JR, et al. 1999 Methods to estimate and analyze medical care resource use. An example from liver transplantation. Int J Technol Assess Health Care. 15: 366– 379.Google Scholar
Kesteloot K, Demoulin L, Penninckx F. 1996 Costing methodology in laparoscopic surgery. Acta Chir Belg. 96: 252– 260.Google Scholar
Linet MS, Harlow SD, McLaughlin JK, et al. 1989 A comparison of interview data and medical records for previous medical conditions and surgery. J Clin Epidemiol. 42: 1207– 1213.Google Scholar
Lyman GH. 2001 Economic analysis of randomized, controlled trials. Curr Oncol Rep. 3: 396– 403.Google Scholar
Mauskopf J, Schulman K, Bell L, et al. 1996 A strategy for collecting pharmacoeconomic data during phase II/III clinical trials. Pharmacoeconomics. 9: 264– 277.Google Scholar
Musser DJ, Boorse RC, Madera F, et al. 1994 Laparoscopic colectomy: At what cost? Surg Laparosc Endosc. 4: 1– 5.Google Scholar
Newman RM, Traverso LW. 1999 Cost-effective minimally invasive surgery: What procedures make sense? World J Surg. 23: 415– 421.Google Scholar
Norrish A, North D, Kirkman P, et al. 1994 Validity of self-reported hospital admission in a prospective study. Am J Epidemiol. 140: 938– 942.Google Scholar
Ota DM. 1997 Colon cancer. Cancer Treat Res. 90: 347– 356.Google Scholar
Petrou S, Murray L, Cooper P, et al. 2002 The accuracy of self-reported healthcare resource utilization in health economic studies. Int J Technol Assess Health Care. 18: 705– 710.Google Scholar
Pfeifer J, Wexner SD, Reissman P, et al. 1995 Laparoscopic vs open colon surgery. Costs and outcome. Surg Endosc. 9: 1322– 1326.Google Scholar
Philipson BM, Bokey EL, Moore JW, et al. 1997 Cost of open versus laparoscopically assisted right hemicolectomy for cancer. World J Surg. 21: 214– 217.Google Scholar
Ramsey SD, McIntosh M, Sullivan SD. 2001 Design issues for conducting cost-effectiveness analyses alongside clinical trials. Annu Rev Public Health. 22: 129– 141.Google Scholar
Reuben DB, Wong RC, Walsh KE, et al. 1995 Feasibility and accuracy of a postcard diary system for tracking healthcare utilization of community-dwelling older persons. J Am Geriatr Soc. 43: 550– 552.Google Scholar
Roberts RO, Bergstralh EJ, Schmidt L, et al. 1996 Comparison of self-reported and medical record health care utilization measures. J Clin Epidemiol. 49: 989– 995.Google Scholar
Senagore AJ, Luchtefeld MA, Mackeigan JM, et al. 1993 Open colectomy versus laparoscopic colectomy: Are there differences? Am Surg. 59: 549– 553, discussion 553-554.Google Scholar
Severens JL, Mulder J, Laheij RJ, et al. 2000 Precision and accuracy in measuring absence from work as a basis for calculating productivity costs in The Netherlands. Soc Sci Med. 51: 243– 249.Google Scholar
Stocchi L, Nelson H. 1998 Laparoscopic colectomy for colon cancer: Trial update. J Surg Oncol. 68: 255– 267.Google Scholar