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Ambulatory Cardiac Monitoring for the Evaluation of Antiarrhythmic Agents

Published online by Cambridge University Press:  10 March 2009

Alexia Antczak-Bouckoms ,
J. F. C. Tulloch  and
Miriam E. Adams
Alexia Antczak-Bouckoms
Affiliation:
Harvard School of Public Health
J. F. C. Tulloch
Affiliation:
University of North Carolina School of Dentistry
Miriam E. Adams
Affiliation:
Harvard School of Public Health
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Abstract

This decision-analysis model assesses ambulatory cardiac monitoring (ACM), ACM followed by exercise testing, and electrophysiologic studies (EPS) in the evaluation and selection of antiarrhythmic agents in postinfarct patients with malignant arrhythmias. With existing data, we find no consistent advantage for one method of drug testing over another, although ACM appears to require fewer resources than does EPS. More patients qualify for EPS, but this fact does not increase the proportion of patients for whom a drug can be identified. These methods may test different aspects of arrhythmia activity and drug response, and sequential use may provide additional benefits. Such benefits must be determined empirically.

Type
General Essays
Information
International Journal of Technology Assessment in Health Care , Volume 9 , Issue 1 , Winter 1993 , pp. 124 - 138
Copyright
Copyright © Cambridge University Press 1993

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