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Searching for Consensus Through Multicriteria Decision Analysis

Assessment of Screening Strategies for Hemoglobinopathies in Southeastern France

Published online by Cambridge University Press:  10 March 2009

Catherine Le Gales  and
Jean-Paul Moatti
Catherine Le Gales
Affiliation:
INSERM
Jean-Paul Moatti
Affiliation:
INSERM
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Abstract

Until now, no systematic strategy for the prevention of major hemoglobinopathies has been implemented in southeastern France, in spite of frequencies of β-thalassemia trait and HbS trait as high as 2·5–8% in some ethnic populations. The purpose of the study was to help a group of experts, brought together by the Regional Center for Disease Control, to reach a consensus about screening for carriers of heterozygote hemoglobinopathies. A multicriteria decision-analysis model was used to take into account not only the costs and effectiveness of potential screening strategies, but also five other qualitative criteria: technical and practical feasibilities, ethical acceptability, information follow-up in time, and global impact on health education. Conclusions differ significatively from those of a pure costeffectiveness analysis, but a multicriteria approach seems best suited to medical experts' preferences.

Type
General Essays
Information
International Journal of Technology Assessment in Health Care , Volume 6 , Issue 3 , April 1990 , pp. 430 - 449
Copyright
Copyright © Cambridge University Press 1990

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References

REFERENCES

1Angastiniotis, M. A., & Hadgiminas, M. G.Prevention of thalassaemia in Cyprus. Lancet, 1981, i, 369–70.CrossRefGoogle Scholar
2Cao, A. et al. , Prevention of homozygous β-thalassaemia by carrier screening and prenatal diagnosis in Sardinia. American Journal of Human Genetics, 1981, 33, 592–605.Google ScholarPubMed
3Glover, R., Shahidi, S., Fisher, B. et al. , Current sickle cell screening program for newborns in New York City 1979–1980. Public Health, 1983, 73, 249–52.Google Scholar
4Institut National de la Statistique et des Etudes Economiques (INSEE). Exploitation par lieu et pays de naissance du fichier Etat-Civil des Mariages de 1982 dans les Bouchesdu-Rhône.Google Scholar
5Institut National de la Statistique et des Etudes Economiques (INSEE). Exploitation par lieu et pays de naissance des parents du fichier Etat-Civil des Naissances de 1982 dans les Bouches du Rhône.Google Scholar
6Keeney, R. L., & Raiffa, H.Decisions with multiple objectives:Preferences and value tradeoffs. New York: Wiley. 1976.Google Scholar
7Modell, B., and Berdoukas, V.The clinical approach to thalassaemia. London: Grune & Stratton, 1984.Google Scholar
8Nussbaum, R. L. et al. , Newborn screening for sickling haemoglobinopathies. American Journal of Diseases of Children, 1984, 138, 44–8.CrossRefGoogle Scholar
9Observatoire Régional de la Santé Provence Alpes Côte d'Azur. Enquête 1986 sur la surveillance périnatale dans la region Provence-Alpes Côte d'Azur (to be published).Google Scholar
10Orsini, A., Vovan, L., Lena-Russo, D. et al. , Dépistage scolaire des hémoglobinoses dans la région marseillaise, étude analytique de 35,289 examens. Archives Françaises de Pédiatrie, 1987, 44, 455–59.Google Scholar
11Roy, B.Méthode multicritère d'aide à la décision. Paris: Economica Eds., 1985.Google Scholar
12Roy, B., & Vincke, P.Multicriteria analysis: Survey and new directions. European Journal of Operational Research, 1981, 8, 207–18.CrossRefGoogle Scholar
13Vovan, L., Lena-Russo, D., & Orsini, A.Diagnostic biologique des hémoglobinoses (Biologic diagnosis of haemoglobin anomalies). Annales de Pédiatrie, 1985, 32, 780–89.Google Scholar
14Weatherall, D. J.The new genetics and clinical practice, 2nd ed, Oxford: Oxford University Press, 1985.Google Scholar
15Weatherall, D. J., & Clegg, J. B.The thalassaemia syndromes, 3rd ed.Oxford: Blackwell Scientific Publications, 1981.Google Scholar
16World Health Organization.Community control of hereditary anaemias: Memorandum from a WHO meeting. Bulletin of the World Health Organization, 1983, 61, 63–80.Google Scholar
17Estimation based on data from “Association Francaise pour le Dépistage et la Prévention des Maladies Métabologiques et des Handicaps de l'Enfant,” Paris.Google Scholar