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Life's chirality from prebiotic environments

Published online by Cambridge University Press:  02 October 2012

Marcelo Gleiser  and
Sara Imari Walker
Marcelo Gleiser*
Affiliation:
Department of Physics and Astronomy, Dartmouth College, Hanover, NH 03755, USA
Sara Imari Walker
Affiliation:
NASA Astrobiology Institute, USA BEYOND: Center for Fundamental Concepts in Science, Arizona State University, Tempe, AZ 85287, USA
*
e-mail: [email protected]
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Abstract

A key open question in the study of life is the origin of biomolecular homochirality: almost every life-form on Earth has exclusively levorotary amino acids and dextrorotary sugars. Will the same handedness be preferred if life is found elsewhere? We review some of the pertinent literature and discuss recent results suggesting that life's homochirality resulted from sequential chiral symmetry breaking triggered by environmental events. In one scenario, autocatalytic prebiotic reactions undergo stochastic fluctuations due to environmental disturbances, in a mechanism reminiscent of evolutionary punctuated equilibrium: short-lived destructive events may lead to long-term enantiomeric excess. In another, chiral-selective polymerization reaction rates influenced by environmental effects lead to substantial chiral excess even in the absence of autocatalysis. Applying these arguments to other potentially life-bearing platforms has implications to the search for extraterrestrial life: we predict that a statistically representative sampling of extraterrestrial stereochemistry will be racemic (chirally neutral) on average.

Keywords

SPASA 2011astrobiologychiralityprebiotic chemistryorigin of life
Type
Research Article
Information
International Journal of Astrobiology , Volume 11 , Issue 4: SPECIAL ISSUE: THE SAO PAULO ADVANCED SCHOOL OF ASTROBIOLOGY – SPASA 2011 , October 2012 , pp. 287 - 296
Copyright
Copyright © Cambridge University Press 2012

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