Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-23T06:49:14.275Z Has data issue: false hasContentIssue false

Use of Antibiotics Reserved for Resistant Gram-Negative Infections at Freestanding U.S. Children’s Hospitals from 2004 to 2014

Published online by Cambridge University Press:  03 May 2016

Monika Jelic
Affiliation:
School of Medicine, University of Washington, Seattle, Washington
Amanda L. Adler
Affiliation:
Seattle Children’s Research Institute, Seattle, Washington
Arianna Miles-Jay
Affiliation:
Department of Epidemiology, University of Washington, Seattle, Washington Seattle Children’s Research Institute, Seattle, Washington
Scott J. Weissman
Affiliation:
Department of Pediatrics, University of Washington, Seattle, Washington Seattle Children’s Research Institute, Seattle, Washington
Matthew P. Kronman
Affiliation:
Department of Pediatrics, University of Washington, Seattle, Washington Seattle Children’s Research Institute, Seattle, Washington
Danielle M. Zerr*
Affiliation:
Department of Pediatrics, University of Washington, Seattle, Washington Seattle Children’s Research Institute, Seattle, Washington
*
Address correspondence to Danielle M Zerr, 4800 Sandpoint Way NE, Seattle, WA 98105 ([email protected]).

Abstract

We used the Pediatric Health Information System database to assess the use of antibiotics reserved for the treatment of resistant Gram-negative infections in children from 2004 to 2014. Overall, use of these agents increased in children from 2004 to 2007 and subsequently decreased.

Infect Control Hosp Epidemiol 2016:37:967–970

Type
Concise Communications
Copyright
© 2016 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Boucher, HW, Talbot, GH, Bradley, JS, et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 2009;48:112.Google Scholar
2. Antibiotic Resistance Threats in the United States 2013, http://www.cdc.gov/drugresistance/threat-report-2013/. Published 2013. Accessed March 14, 2014.Google Scholar
3. Logan, LK, Braykov, NP, Weinstein, RA, Laxminarayan, R, Program CDCEP. Extended-spectrum beta-lactamase-producing and third-generation cephalosporin-resistant enterobacteriaceae in children: trends in the United States, 1999–2011. J Pediatric Infect Dis Soc 2014;3:320328.Google Scholar
4. Hsu, AJ, Tamma, PD. Treatment of multidrug-resistant Gram-negative infections in children. Clin Infect Dis 2014;58:14391448.Google Scholar
5. Qin, X, Galanakis, E, Zerr, DM, Weissman, SJ. Antibiotic options for treatment of pediatric infections with enterobacteriaceae producing broad spectrum beta-lactamases. Antiinfect Agents 2015;10:130135.Google Scholar
6. Kadri, SS, Hohmann, SF, Orav, EJ, et al. Tracking colistin-treated patients to monitor the incidence and outcome of carbapenem-resistant Gram-negative infections. Clin Infect Dis 2015;60:7987.Google Scholar
7. Tamma, PD, Newland, JG, Pannaraj, PS, et al. The use of intravenous colistin among children in the United States: results from a multicenter, case series. Pediatr Infect Dis J 2013;32:1722.CrossRefGoogle ScholarPubMed
8. Hersh, AL, De Lurgio, SA, Thurm, C, et al. Antimicrobial stewardship programs in freestanding children’s hospitals. Pediatrics 2015;135:3339.Google Scholar
9. Feudtner, C, Feinstein, JA, Zhong, W, Hall, M, Dai, D. Pediatric complex chronic conditions classification system version 2: updated for ICD-10 and complex medical technology dependence and transplantation. BMC Pediatr 2014;14:199.CrossRefGoogle ScholarPubMed
10. Dellit, TH, Owens, RC, McGowan, JE Jr, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007;44:159177.Google Scholar