Hostname: page-component-cd9895bd7-p9bg8 Total loading time: 0 Render date: 2024-12-23T08:39:47.569Z Has data issue: false hasContentIssue false
  • English
  • Français

A Successful Vancomycin-Resistant Enterococci Reduction Bundle at a Singapore Hospital

Published online by Cambridge University Press:  21 October 2015

Dale Fisher ,
Long Pang ,
Sharon Salmon ,
Raymond T.P. Lin ,
Cathrine Teo ,
Paul Tambyah ,
Roland Jureen ,
Alex R. Cook  and
Jonathan A. Otter
Dale Fisher*
Affiliation:
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Division of Infectious Diseases, University Medicine Cluster, National University Health System, Singapore, Singapore
Long Pang
Affiliation:
Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore
Sharon Salmon
Affiliation:
Department of Nursing Administration, National University Health System, Singapore, Singapore
Raymond T.P. Lin
Affiliation:
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Department of Laboratory Medicine, National University Health System, Singapore, Singapore
Cathrine Teo
Affiliation:
Department of Nursing Administration, National University Health System, Singapore, Singapore
Paul Tambyah
Affiliation:
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore Division of Infectious Diseases, University Medicine Cluster, National University Health System, Singapore, Singapore
Roland Jureen
Affiliation:
Department of Laboratory Medicine, National University Health System, Singapore, Singapore
Alex R. Cook
Affiliation:
Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore
Jonathan A. Otter
Affiliation:
Imperial College Healthcare NHS Trust, London, UK.
*
Address correspondence to Professor Dale Fisher, NUHS Tower Block, 1E Kent Ridge Road, Level 10, Singapore, Singapore 119228 ([email protected]).
Get access Rights & Permissions [Opens in a new window]

Abstract

We report a reduction in the vancomycin-resistant enterococci (VRE) rate from a peak of 1.5 cases per 1,000 admissions (95% confidence interval [CI], 1.0−2.1) in August 2012 to 0.5 per 1,000 admissions (95% CI: 0.3−1.0) by January 2015, associated with a bundle of interventions.

Infect. Control Hosp. Epidemiol. 2015;37(1):107–109

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 37 , Issue 1 , January 2016 , pp. 107 - 109
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Humphreys, H. Controlling the spread of vancomycin-resistant enterococci. Is active screening worthwhile? J Hosp Infect 2014;88:191–198.CrossRefGoogle ScholarPubMed
2. Cai, Y, Chan, JP, Fisher, DA, et al. Vancomycin-resistant enterococci in singaporean hospitals: 5-year results of a multi-centre surveillance programme. Ann Acad Med Singapore 2012;41:77–81.CrossRefGoogle ScholarPubMed
3. Passaretti, CL, Otter, JA, Reich, NG, et al. An evaluation of environmental decontamination with hydrogen peroxide vapor for reducing the risk of patient acquisition of multidrug-resistant organisms. Clin Infect Dis 2013;56:27–35.CrossRefGoogle ScholarPubMed
4. Hayden, MK, Bonten, MJ, Blom, DW, Lyle, EA, van de Vijver, DA, Weinstein, RA. Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures. Clin Infect Dis 2006;42:1552–1560.Google Scholar
5. Diekema, DJ, Edmond, MB. Look before you leap: active surveillance for multidrug-resistant organisms. Clin Infect Dis 2007;44:1101–1107.Google ScholarPubMed
6. Otter, JA, Yezli, S, French, GL. The role played by contaminated surfaces in the transmission of nosocomial pathogens. Infect Control Hosp Epidemiol 2011;32:687–699.Google Scholar
7. Gelman, A, Shalizi, CR. Philosophy and the practice of Bayesian statistics. Br J Math Stat Psychol 2013;66:8–38.Google Scholar
8. R development core team. R: A language and environment for statistical computing. Vienna, Austria: R foundation for statistical computing. R Project Web site. http://www.R-project.Org. Published 2010. Accessed September 2015.Google Scholar
9. Dutka-Malen, S, Evers, S, Courvalin, P. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by pcr. J Clin Microbiol 1995;33:24–27.CrossRefGoogle Scholar
10. Top, J, Schouls, LM, Bonten, MJ, Willems, RJ. Multiple-locus variable-number tandem repeat analysis, a novel typing scheme to study the genetic relatedness and epidemiology of Enterococcus faecium isolates. J Clin Microbiol 2004;42:4503–4511.CrossRefGoogle Scholar
11. Carling, PC, Parry, MM, Rupp, ME, Po, JL, Dick, B, Von Beheren, S. Improving cleaning of the environment surrounding patients in 36 acute care hospitals. Infect Control Hosp Epidemiol 2008;29:1035–1041.Google Scholar
12. Johnson, PD, Ballard, SA, Grabsch, EA, et al. A sustained hospital outbreak of vancomycin-resistant Enterococcus faecium bacteremia due to emergence of vanb e. Faecium sequence type 203. J Infect Dis 2010;202:1278–1286.Google Scholar