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Standard versus combined chemical, mechanical, and heat decontamination of hospital drains harboring carbapenemase-producing organisms (CPOs): A randomized controlled trial

Published online by Cambridge University Press:  08 February 2021

Alainna J. Jamal
Affiliation:
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Sinai Health System, Toronto, Ontario, Canada
Rajni Pantelidis
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Rachael Sawicki
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Angel X. Li
Affiliation:
Sinai Health System, Toronto, Ontario, Canada
Wayne Chiu
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Deborah Morrison
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
John Marshman
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Mahin Baqi
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
David Richardson
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Allison J. McGeer*
Affiliation:
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Sinai Health System, Toronto, Ontario, Canada
Sergio Borgia
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
*
Author for correspondence: Allison J. McGeer, E-mail: [email protected]

Abstract

We sought to determine whether combined chemical, mechanical, and heat cleaning was superior to standard cleaning for the decontamination of 32 sink and shower drains harboring carbapenemase-producing organisms (CPOs). Of 16 intervention drains, 10 (63%) were decontaminated until day 7 versus 1 (5%) of 16 comparator drains (P = .002). Intensive cleaning may be useful if administered repeatedly in drain-associated CPO outbreaks.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

PREVIOUS PRESENTATION. Preliminary data were accepted for presentation at the CDC/SHEA Decennial Meeting (abstract no. 741) scheduled for March 2020; the meeting was cancelled due to COVID-19.

References

Nordmann, P, Naas, T, Poirel, L. Global spread of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis 2011;17:17911798.CrossRefGoogle ScholarPubMed
Kizny Gordon, AE, Mathers, AJ, Cheong, EYL, et al. The hospital water environment as a reservoir for carbapenem-resistant organisms causing hospital-acquired infections—a systematic review of the literature. Clin Infect Dis 2017;64:14361444.CrossRefGoogle ScholarPubMed
Carling, PC. Wastewater drains: epidemiology and interventions in 23 carbapenem-resistant organism outbreaks. Infect Control Hosp Epidemiol 2018;39:972979.CrossRefGoogle ScholarPubMed
Parkes, LO, Hota, SS. Sink-related outbreaks and mitigation strategies in healthcare facilities. Curr Infect Dis Rep 2018;20(10):42.CrossRefGoogle ScholarPubMed
Jamal, AJ, Garcia-Jeldes, F, Baqi, M, et al. Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada. Infect Control Hosp Epidemiol 2019;40:10061012.CrossRefGoogle ScholarPubMed
Jamal, AJ, Mataseje, L, Brown, K, et al. Carbapenemase-producing Enterobacterales (CPE) in hospital drains in Ontario, Canada. J Hosp Infect 2020;106:820827.CrossRefGoogle ScholarPubMed
Tijet, N, Patel, S, Melano, RG. Detection of carbapenemase activity in Enterobacteriaceae: comparison of the carbapenem inactivation method versus the Carba NP test. J Antimicrob Chemother 2016;71:274276.CrossRefGoogle ScholarPubMed
M100 Performance Standards for Antimicrobial Susceptibility Testing, 29th Edition. Clinical and Laboratory Standards Institute website. https://clsi.org/media/2663/m100ed29_sample.pdf. Published 2019. Accessed June 15, 2020.Google Scholar
Grabowski, M, Lobo, JM, Gunnell, B, et al. Characterizations of handwashing sink activities in a single hospital medical intensive care unit. J Hosp Infect 2018;100:e115e122.CrossRefGoogle Scholar
Kotay, S, Chai, W, Guilford, W, Barry, W, Barry, K, Mathers, A. Spread from the sink to the patient: in situ study using green fluorescent protein (GFP)-expressing Escherichia coli to model bacterial dispersion from hand-washing sink-trap reservoirs. Appl Env Microbiol 2017;83:112.CrossRefGoogle ScholarPubMed
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