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Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) outbreaks in nursing homes involving residents who had completed a primary coronavirus disease 2019 (COVID-19) vaccine series—13 US jurisdictions, July–November 2021

Published online by Cambridge University Press:  16 January 2023

W. Wyatt Wilson Open the ORCID record for W. Wyatt Wilson [Opens in a new window] ,
Amelia A. Keaton ,
Lucas G. Ochoa Open the ORCID record for Lucas G. Ochoa [Opens in a new window] ,
Kelly M. Hatfield ,
Paige Gable Open the ORCID record for Paige Gable [Opens in a new window] ,
Kelly A. Walblay ,
Richard A. Teran Open the ORCID record for Richard A. Teran [Opens in a new window] ,
Meghan Shea ,
Urooj Khan  and
Ginger Stringer Open the ORCID record for Ginger Stringer [Opens in a new window]
...Show all authors
W. Wyatt Wilson*
Affiliation:
Epidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Amelia A. Keaton
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Lucas G. Ochoa
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Kelly M. Hatfield
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Paige Gable
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Kelly A. Walblay
Affiliation:
Chicago Department of Public Health, Chicago, Illinois
Richard A. Teran
Affiliation:
Epidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia Chicago Department of Public Health, Chicago, Illinois
Meghan Shea
Affiliation:
Colorado Department of Public Health and Environment, Denver, Colorado
Urooj Khan
Affiliation:
Colorado Department of Public Health and Environment, Denver, Colorado
Ginger Stringer
Affiliation:
Colorado Department of Public Health and Environment, Denver, Colorado
Joanne G. Colletti
Affiliation:
Connecticut Department of Public Health, Hartford, Connecticut
Erin M. Grogan
Affiliation:
Connecticut Department of Public Health, Hartford, Connecticut
Carly Calabrese
Affiliation:
Iowa Department of Public Health, Des Moines, Iowa
Andrew Hennenfent
Affiliation:
Iowa Department of Public Health, Des Moines, Iowa
Rebecca Perlmutter
Affiliation:
Maryland Department of Health, Baltimore, Maryland
Katherine A. Janiszewski
Affiliation:
Massachusetts Department of Public Health, Jamaica Plain, Massachusetts
Ishrat Kamal-Ahmed
Affiliation:
Nebraska Department of Health and Human Services, Lincoln, Nebraska
Kyle Strand
Affiliation:
Nebraska Department of Health and Human Services, Lincoln, Nebraska
Emily Berns
Affiliation:
North Carolina Department of Health and Human Services, Raleigh, North Carolina
Jennifer MacFarquhar
Affiliation:
North Carolina Department of Health and Human Services, Raleigh, North Carolina Division of State and Local Readiness, Center for Preparedness and Response, CDC, Atlanta, Georgia
Meghan Linder
Affiliation:
Oregon Health Authority, Portland, Oregon
Dat J. Tran
Affiliation:
Oregon Health Authority, Portland, Oregon
Patricia Kopp
Affiliation:
South Carolina Department of Health and Environmental Control, Columbia, South Carolina
Rebecca M. Walker
Affiliation:
South Carolina Department of Health and Environmental Control, Columbia, South Carolina
Rebekah Ess
Affiliation:
Utah Department of Health, Salt Lake City, Utah
Jennifer S. Read
Affiliation:
Vermont Department of Health, Burlington, Vermont
Chelsey Yingst
Affiliation:
West Virginia Department of Health and Human Resources, Charleston, West Virginia
James Baggs
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
John A. Jernigan
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Alex Kallen
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
Jennifer C. Hunter
Affiliation:
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia
*
Author for correspondence: W. Wyatt Wilson, E-mail: [email protected]
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Abstract

Among nursing home outbreaks of coronavirus disease 2019 (COVID-19) with ≥3 breakthrough infections when the predominant severe acute respiratory coronavirus virus 2 (SARS-CoV-2) variant circulating was the SARS-CoV-2 δ (delta) variant, fully vaccinated residents were 28% less likely to be infected than were unvaccinated residents. Once infected, they had approximately half the risk for all-cause hospitalization and all-cause death compared with unvaccinated infected residents.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 6 , June 2023 , pp. 1005 - 1009
Creative Commons
To the extent this is a work of the US Government, it is not subject to copyright protection within the United States. To the extent this work is subject to copyright outside of the United States, such copyright shall be assigned to The Society for Healthcare Epidemiology of America and licenced to the Publisher. Outside of the United States, the US Government retains a paid-up, non-exclusive, irrevocable worldwide license to reproduce, prepare derivative works, distribute copies to the public and display publicly the Contribution, and to permit others to do so. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.
Copyright
© The Society for Healthcare Epidemiology of America, 2023

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Footnotes

Monitoring Outbreaks of Variants in Nursing Homes (MOVIN) Surveillance Team: Hira Adil MBBS3, Stephanie R. Black MD3, Daniel Galanto MPH3, Marie Heppe BS3, Elizabeth Shane MPH3, Winter Viverette MAIO3, Shannon N. Xydis BS3, Christy Zelinski MPH3, Carly Lipke BS4, Brooke McCain MPH4, Brandi Tolle MPH4, Wesley Hottel PhD6, Valérie Webb PhD6, Christina Brandeburg MPH8, Meagan Burns MPH8, Timelia Fink MPH8, Melissa Cumming MPH8, Matthew Doucette BS8, Glen Gallagher PhD8, Andrew Lang PhD8, M. Salman Ashraf MBBS9, Kevin Cueto MPH9, Matthew Donahue MD9, Jonathan Figliomeni MPH9, Alexander Vasa MPH9, Amanda E. Faulkner MPH12, Rebecca Pierce PhD12, Megan Davis MS13, Jennifer L. Donehue MPH13, Christy Greenwood BS13, Terri Hannibal MSN13, Alison Jamison-Haggwood MSN13, LaKita D. Johnson MPH13, Rachel A. Radcliffe DVM13 and Hannah V. Ruegner MPH13

References

Dougherty, K, Mannell, M, Naqvi, O, Matson, D, Stone, J. SARS-CoV-2 B.1.617.2 (delta) variant COVID-19 outbreak associated with a gymnastics facility—Oklahoma, April–May 2021. Morb Mortal Wkly Rep 2021;70:1004–1007.CrossRefGoogle ScholarPubMed
Tartof, SY, Slezak, JM, Fischer, H, et al. Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study. Lancet 2021;398:1407–1416.CrossRefGoogle Scholar
Bialek, S, Boundy, E, Bowen, V, et al. COVID-19 Response Team. Severe outcomes among patients with coronavirus disease 2019 (COVID-19)—United States, February 12–March 16, 2020. Morb Mortal Wkly Rep 2020;69:343–346.Google Scholar
Bajema, KL, Dahl, RM, Prill, MM, et al. Effectiveness of COVID-19 mRNA vaccines against COVID-19–associated hospitalization—five Veterans’ Affairs medical centers, United States, February 1–August 6, 2021. Morb Mortal Wkly Rep 2021;70:1294–1299.CrossRefGoogle ScholarPubMed
Harris-Kojetin, L, Sengupta, M, Lendon, JP, Rome, V, Valverde, R, Caffrey, C. Long-term care providers and services users in the United States, 2015–2016. In: Vital Health Statistics. Atlanta, series 3 no. 43. Atlanta: CDC; 2019.Google Scholar
Nanduri, S, Pilishvili, T, Derado, G, et al. Effectiveness of Pfizer-BioNTech and Moderna vaccines in preventing SARS-CoV-2 infection among nursing home residents before and during widespread circulation of the SARS-CoV-2 B.1.617.2 (delta) variant—National Healthcare Safety Network, March 1–August 1, 2021. Morb Mortal Wkly Rep 2021;70:1163–1166.CrossRefGoogle ScholarPubMed
US Department of Health and Human Services. Science brief: Omicron (B.1.1.529) variant. Centers for Disease Control and Prevention website. https://www.cdc.gov/coronavirus/2019-ncov/science/science-briefs/scientific-brief-omicron-variant.html. Published 2021. Accessed December 15, 2021.Google Scholar
US Department of Health and Human Services. Nursing home COVID-19 vaccination data dashboard. Centers for Disease Control and Prevention website. https://www.cdc.gov/nhsn/covid19/ltc-vaccination-dashboard.html. Published 2021. Accessed December 16, 2021.Google Scholar
US Department of Health and Human Services. Testing: create a plan for testing residents and HCP for SARS-CoV-2. Centers for Disease Control and Prevention website. https://www.cdc.gov/coronavirus/2019-ncov/hcp/long-term-care.html#anchor_1631031062858. Published 2021. Accessed January 13, 2021.Google Scholar
Khoury, DS, Cromer, D, Reynaldi, A, et al. Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nat Med 2021;27:1205–1211.CrossRefGoogle ScholarPubMed