Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-26T22:04:50.587Z Has data issue: false hasContentIssue false

Risk of Nosocomial Transmission of Nipah Virus in a Bangladesh Hospital

Published online by Cambridge University Press:  02 January 2015

Emily S. Gurley*
Affiliation:
Centre for Health and Population Research, ICDDR.B, Dhaka, Bangladesh
Joel M. Montgomery
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
M. Jahangir Hossain
Affiliation:
Centre for Health and Population Research, ICDDR.B, Dhaka, Bangladesh
M. Rafiqul Islam
Affiliation:
Institute of Epidemiology, Disease Control and Research, Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka, Bangladesh
M. Abdur Rahim Molla
Affiliation:
Institute of Epidemiology, Disease Control and Research, Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka, Bangladesh
S. M. Shamsuzzaman
Affiliation:
Institute of Epidemiology, Disease Control and Research, Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka, Bangladesh
Kazi Akram
Affiliation:
World Health Organization, Dhaka, Bangladesh
Kamruz Zaman
Affiliation:
World Health Organization, Dhaka, Bangladesh
Nima Asgari
Affiliation:
World Health Organization, Geneva, Switzerland
James A. Comer
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
Abul Kalam Azad
Affiliation:
Institute of Epidemiology, Disease Control and Research, Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka, Bangladesh
Pierre E. Rollin
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
Thomas G. Ksiazek
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
Robert F. Breiman
Affiliation:
Centre for Health and Population Research, ICDDR.B, Dhaka, Bangladesh
*
Programme on Infectious Diseases and Vaccine Sciences, Centre for Health and Population Research, ICDDR.B, Mohakhali, Dhaka 1212, Bangladesh ([email protected])

Abstract

We conducted a seroprevalence study and exposure survey of healthcare workers to assess the risk of nosocomial transmission of Nipah virus during an outbreak in Bangladesh in 2004. No evidence of recent Nipah virus infection was detected despite substantial exposures and minimal use of personal protective equipment.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Chua, KB, Goh, KJ, Wong, KT, et al.Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia. Lancet 1999;354:12571259.Google Scholar
2.Chua, KB, Lam, SK, Goh, KJ, et al.The presence of Nipah virus in respiratory secretions and urine of patients during and outbreak of Nipah virus encephalitis in Malaysia. J Infect 2001;42:4043.Google Scholar
3.Lam, SK, Chua, KB. Nipah virus encephalitis outbreak in Malaysia. Clin Infect Dis 2002;34(suppl 2): S48S51.Google Scholar
4.Paton, NI, Leo, YS, Zaki, SR, et al.Outbreak of Nipah virus infection among abattoir workers in Singapore. Lancet 1999;354:12531256.CrossRefGoogle ScholarPubMed
5.Chua, KB. Nipah virus outbreak in Malaysia. J Clin Virol 2003;26:265275.Google Scholar
6.Sahani, M, Parashar, UD, Ali, R, et al.Nipah virus infection among abattoir workers in Malaysia, 1998-1999. Int J Epidemiol 2001;30:10171020.Google Scholar
7.Harcourt, BH, Lowe, L, Tamin, A, et al.Genetic characterization of Nipah virus, Bangladesh, 2004. Emerg Infect Dis 2005;11:15941597.Google Scholar
8.Mounts, AW, Kaur, H, Parashar, UD, et al.A cohort study of health care workers to assess nosocomial transmissibility of Nipah virus, Malaysia, 1999. J Infect Dis 2001;183:810813.Google Scholar
9.Chadha, MS, Comer, JA, Lowe, L, et al.Nipah virus-associated encephalitis outbreak, Siliguri, India. Emerg Infect Dis 2006;12:235240.CrossRefGoogle ScholarPubMed
10.Hsu, VP, Hossain, MJ, Parashar, UD, et al.Nipah virus encephalitis re-emergence, Bangladesh. Emerg Infect Dis 2004;10:20822087.CrossRefGoogle Scholar
11.Tan, CT, Tan, KS. Nosocomial transmissibility of Nipah virus. J Infect Dis 2001;184:1367.CrossRefGoogle ScholarPubMed
12.Garner, JS. Guidelines for isolation precautions in hospitals: the Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 1996;17:5380.CrossRefGoogle ScholarPubMed
13.ICDDR.B. Nipah encephalitis outbreak over wide area of western Bangladesh, 2004. Health Sci Bull 2004;2:711. Available at: http://www.icddrb.org. Accessed May 8, 2007.Google Scholar
14.Gurley, ES, Montgomery, JM, Hossain, MJ, et al.Person-to-person transmission of Nipah virus in a Bangladeshi community. Emerg Infect Dis 2007. In press.Google Scholar
15.Daniels, P, Ksiazek, T, Eaton, BT. Laboratory diagnosis of Nipah and Hen-dra virus infections. Microbes Infect 2001;3:289295.Google Scholar
16.Goh, KJ, Tan, CT, Chew, NK, et al.Clinical features of Nipah virus encephalitis among pig farmers in Malaysia. N Engl J Med 2000;342:12291235.Google Scholar
17.Ramasundrum, V, Tan, CT, Chua, KB, et al.Kinetics of IgM and IgG seroconversion in Nipah virus infection. Neurol J Southeast Asia 2000;5:2328.Google Scholar
18.Pruss-Ustun, A, Rapiti, E, Hutin, Y. Estimation of the global burden of disease attributable to contaminated sharps injuries among health-care workers. Am J Ind Med 2005;48:482490.CrossRefGoogle ScholarPubMed
19.Mujeeb, SA, Khatri, Y, Khanami, R. Frequency of parenteral exposure and seroprevalence if HBV, HCV, and HIV among operation room personnel. J Hosp Infect 1998;38:133137.CrossRefGoogle ScholarPubMed