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Risk Factors for Development of Intestinal Colonization with Imipenem-Resistant Pseudomonas aeruginosa in the Intensive Care Unit Setting

Published online by Cambridge University Press:  02 January 2015

Anthony D. Harris ,
J. Kristie Johnson ,
Kerri A. Thom ,
Daniel J. Morgan ,
Jessina C. McGregor ,
Adebola O. Ajao ,
Anita C. Moore ,
Angela C. Comer  and
Jon P. Furuno
Anthony D. Harris*
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
J. Kristie Johnson
Affiliation:
Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland
Kerri A. Thom
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Daniel J. Morgan
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Jessina C. McGregor
Affiliation:
College of Pharmacy, Oregon State University/Oregon Health and Science University, Portland, Oregon
Adebola O. Ajao
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Anita C. Moore
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Angela C. Comer
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Jon P. Furuno
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
*
University of Maryland School of Medicine, Department of Epidemiology and Public Health, 685 West Baltimore Street, Room 330, Baltimore, MD 21201 ([email protected])
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Extract

Risk factors for development of intestinal colonization by imipenem-resistant Pseudomonas aeruginosa (IRPA) may differ between those who acquire the organism via patient-to-patient transmission versus by antibiotic selective pressure. The aim of this study was to quantify potential risk factors for the development of IRPA not due to patient-to-patient transmission.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 32 , Issue 7 , July 2011 , pp. 719 - 722
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

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References

1.Hidron, AI, Edwards, JR, Patel, J, et al. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007. Infect Control Hosp Epidemiol 2008;29:996–1011.Google Scholar
2.Bonten, MJ, Slaughter, S, Ambergen, AW, et al. The role of “colonization pressure” in the spread of vancomycin-resistant enterococci: an important infection control variable. Arch Intern Med 1998;158:1127–1132.CrossRefGoogle ScholarPubMed
3.Lepelletier, D, Caroff, N, Riochet, D, et al. Role of hospital stay and antibiotic use on Pseudomonas aeruginosa gastrointestinal colonization in hospitalized patients. Eur J Clin Microbiol Infect Dis 2006;25:600–603.CrossRefGoogle ScholarPubMed
4.Pena, C, Guzman, A, Suarez, C, et al. Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients. Antimicrob Agents Chemother 2007;51:1967–1971.Google Scholar
5.Johnson, JK, Smith, G, Lee, MS, et al. The role of patient-to-patient transmission in the acquisition of imipenem-resistant Pseudomonas aeruginosa colonization in the intensive care unit. J Infect Dis 2009;200:900–905.CrossRefGoogle ScholarPubMed
6.Harris, AD, Karchmer, TB, Carmeli, Y, Samore, MH. Methodological principles of case-control studies that analyzed risk factors for antibiotic resistance: a systematic review. Clin Infect Dis 2001;32:1055–1061.CrossRefGoogle ScholarPubMed
7.Lankford, MG, Collins, S, Youngberg, L, Rooney, DM, Warren, JR, Noskin, GA. Assessment of materials commonly utilized in health care: implications for bacterial survival and transmission. Am J Infect Control 2006;34:258–263.Google Scholar
8.Panagea, S, Winstanley, C, Walshaw, MJ, Ledson, MJ, Hart, CA. Environmental contamination with an epidemic strain of Pseudomonas aeruginosa in a Liverpool cystic fibrosis centre, and study of its survival on dry surfaces. J Hosp Infect 2005;59:102–107.Google Scholar
9.Kollef, MH. Broad-spectrum antimicrobials and the treatment of serious bacterial infections: getting it right up front. Clin Infect Dis 2008;47(suppl 1):S3–S13.CrossRefGoogle ScholarPubMed
10.Thom, KA, Johnson, JA, Strauss, SM, Furuno, JP, Perencevich, EN, Harris, AD. Increasing prevalence of gastrointestinal colonization with ceftazidime-resistant gram-negative bacteria among intensive care unit patients. Infect Control Hosp Epidemiol 2007;28:1240–1246.Google Scholar