Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-25T04:08:41.021Z Has data issue: false hasContentIssue false

Reduction in Clostridium difficile Infections among Neurosurgical Patients Associated with Discontinuation of Antimicrobial Prophylaxis for the Duration of External Ventricular Drain Placement

Published online by Cambridge University Press:  10 May 2016

Timothy H. Dellit*
Affiliation:
Department of Infection Control, Harborview Medical Center, Seattle, Washington
Jeannie D. Chan
Affiliation:
Department of Infection Control, Harborview Medical Center, Seattle, Washington
Charlotte Fulton
Affiliation:
Department of Infection Control, Harborview Medical Center, Seattle, Washington
Ronald F. Pergamit
Affiliation:
Department of Infection Control, Harborview Medical Center, Seattle, Washington
Elizabeth A. McNamara
Affiliation:
Department of Infection Control, Harborview Medical Center, Seattle, Washington
Louis J. Kim
Affiliation:
Department of Neurological Surgery, Harborview Medical Center, Seattle, Washington
Richard G. Ellenbogen
Affiliation:
Department of Neurological Surgery, Harborview Medical Center, Seattle, Washington
John B. Lynch
Affiliation:
Department of Infection Control, Harborview Medical Center, Seattle, Washington
*
Harborview Medical Center, 325 9th Avenue, Box 359778, Seattle, WA 98104 ([email protected])

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Briefs
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2014

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Loo, VG, Poirier, L, Miller, MA, et al. A predominantly clonal multi-institutional outbreak of Clostridium diffidle-associated diarrhea with high morbidity and mortality. N Engl J Med 2005;353(23)24422449.Google Scholar
2. McDonald, LC, Lessa, F, Sievert, D, et al. Vital signs: preventing Clostridium difficile infections. Morb Mortal Wkly Rep 2012;61(9):157162.Google Scholar
3. Valiquette, L, Cossette, B, Garant, M-P, Diab, H, Pépin, J. Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium diffidle-associated disease caused by the hypervirulent NAP1/027 strain. Clin Infect Dis 2007;45(suppl 2):S112S121.Google Scholar
4. Prabhu, VC, Kaufman, HH, Voelker, JL, Aronoff, SC, Niewiadom-ska-Bugaj, M, Mascara, S, Hobbs, GR. Prophylactic antibiotics with intracranial pressure monitors and external ventricular drains: a review of the evidence. Surg Neurol 1999;52(3)226237.Google Scholar
5. Wong, GKC, Ip, M, Poon, WS, Mak, CWK, Ng, RYT. Antibiotics-impregnated ventricular catheter versus systemic antibiotics for prevention of nosocomial CSF and non-CSF infections: a prospective randomized clinical trial. J Neurol Neurosurg Psychiatry 2010;81(10)10641067.Google Scholar
6. Sonabend, AM, Korenfeld, Y, Crisman, C, Badjatia, N, Mayer, SA, Connolly, ES Jr. Prevention of ventriculostomy-related infections with prophylactic antibiotics and antibiotic-coated external ventricular drains: a systematic review. Neurosurgery 2011;68(4)9961005.CrossRefGoogle ScholarPubMed
7. Pakyz, AL, MacDougall, C, Oinonen, M, Polk, RE. Trends in antibacterial use in US academic health centers: 2002 to 2006. Arch Intern Med 2008;168(20)22542260.Google Scholar
8. Zabramski, JM, Whiting, D, Darouiche, RO, et al. Efficacy of antimicrobial-impregnated eternal ventricular drain catheters: a prospective, randomized, controlled trial. J Neurosurg 2003;98(4):725730.Google Scholar
9. Muttaiyah, S, Ritchie, S, John, S, Mee, E, Roberts, S. Efficacy of antibiotic-impregnated external ventricular drain catheters. J Clin Neurosci 2010;17(3)296298.Google Scholar