Hostname: page-component-745bb68f8f-hvd4g Total loading time: 0 Render date: 2025-02-02T04:24:55.718Z Has data issue: false hasContentIssue false
  • English
  • Français

Recurrent Meningococcal Meningitis Caused by Poly Groups X-W135: Importance of Chemoprophylaxis

Published online by Cambridge University Press:  02 January 2015

Richard F. Jacobs  and
Terry Yamauchi
Richard F. Jacobs*
Affiliation:
Division of Infectious Disease, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas
Terry Yamauchi
Affiliation:
Division of Infectious Disease, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas
*
Division of Infectious Diseases, Children's Orthopedic Hospital, 4800 Sand Point Way, N.E., Seattle, WA 98105
Get access Rights & Permissions [Opens in a new window]

Abstract

Presented is a case report and literature review of the causes of recurrent meningococcal meningitis. After all factors were analyzed, the cause of reinfection in this child was postulated to be ineffective chemoprophylaxis of close contacts following the initial episode. The efficacy of chemoprophylaxis in household members and close contacts in meningococcal disease, although not demonstrated in controlled trials, has been recommended since 1974 by the Meningococcal Disease Surveillance Group. Considering known carriage rates, reports of secondary infections in close contacts, reinfection in the same person, and a high case fatality ratio, chemoprophylaxis in such cases seems justified [Infect Control 1981; 2(4):312-4.]

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 2 , Issue 4 , August 1981 , pp. 312 - 314
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Hoeprich, PD. Infectious Diseases, ed. 2. New York, Harper and Row, 1977;889–93.Google Scholar
2.Lim, D, et al.Absence of the sixth component of complement in a patient with repeated episodes of meningococcal meningitis. J Pediatr 1976:89:42–7.CrossRefGoogle Scholar
3.Van Peenan, PFD. Second attacks of meningococcal meningitis. Calif Med 1965;103:132–4.Google Scholar
4.Nail, RL. Meningococcal meningitis: Repeat case. N Engl J Med 1970;282:1211.Google ScholarPubMed
5.Vedros, NA, et al.Studies on immunitv in meningococcal meningitis. Milit Med 1966;131:1413–7.CrossRefGoogle Scholar
7.Griffiss, JM, et al.Recurrent meningococcal infection with an antigenically identical strain. JAMA 1974;229:68–70.CrossRefGoogle ScholarPubMed
7.Kenny, JF. Bacterial variants in central nervous system infections in infants and children. J Pediatr 1973;83:531–42.CrossRefGoogle ScholarPubMed
8.Gold, R, et al.Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children. J Infect Dis 1978;137:112–21.CrossRefGoogle ScholarPubMed
9.The Meningococcal Disease Surveillance Groups: Meningococcal disease secondary attack rate and chemoprophylaxis in the USA, 1974. JAMA 1976;235:261–5.CrossRefGoogle Scholar
10.Wenzel, RP, et al.Non-usefulness of meningococcal carriage-rates (letter). Lancet 1973;2:205.CrossRefGoogle Scholar
11.Greenfield, S, Feldman, HA. Familial carriers and meningococcal meningitis. N Engl J Med 1967;277:497–502.CrossRefGoogle ScholarPubMed
12.Hoeprich, PD. Prediction of antimcningococci chemoprophylaxis. J Infect Dis 1971;123:125–33.CrossRefGoogle Scholar
13.Munford, RS, et al.Spread of meningococcal infection in households. Lancet 1974;1:1275–9.CrossRefGoogle ScholarPubMed
14.Artenstein, MS, et al.The risk of exposure to a patient with meningococcal meningitis. Milit Med 1968:133:474–7.CrossRefGoogle ScholarPubMed
15.Jacobson, JA, et al.Trends in meningococcal disease 1974. J Infect Dis 1975;132:480–4.CrossRefGoogle ScholarPubMed
16.Jacobson, JA, et al.Meningococcal disease in day care centers. Pediatrics 1977;59:299–301.CrossRefGoogle ScholarPubMed
17.Deal, WB, Sanders, E. Efficacy of rifampin in treatment of meningococcal carriers. N Engl J Med 1969;281:641–5.CrossRefGoogle ScholarPubMed
18.Guttler, RB, et al.Effect of rifampin and minocycline on meningococcal carrier rates. J Infect Dis 1971;124:199–205.CrossRefGoogle ScholarPubMed
19.Eickhoff, TC. In vitro and in vivo studies of resistance to rifampin in meningococci. J Infect Dist 1971;123:414–7.CrossRefGoogle ScholarPubMed
20.Pickering, LK. Chemoprophylaxis against Neisseria meningitidis. JAMA 1976;236:1882–3.CrossRefGoogle ScholarPubMed
21.Artenstein, MS. Prophylaxis for meningococcal disease. JAMA 1975;231:1035–7.CrossRefGoogle ScholarPubMed
22.Munford, RS, et al.Eradication of carriage of Neisseria meningitidis in families: A study in Brazil. J Infect Dis 1974;129:644–9.CrossRefGoogle ScholarPubMed
23.American Academy of Pediatrics. Report of the Committee on Infectious Diseases, ed. 18. Evanston, IL, American Academy of Pediatrics, 1977;145.Google Scholar