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QuantiFERON-TB Testing for Latent Tuberculosis Infection in Low-Prevalence Countries: Making the Most of an Imperfect Process

Published online by Cambridge University Press:  02 January 2015

William J. Schneider*
Affiliation:
Employee Health and Wellness Services, Memorial Sloan-Kettering Cancer Center, New York, New York Weill Cornell Medical College, New York, New York
Arthur E. Brown
Affiliation:
Employee Health and Wellness Services, Memorial Sloan-Kettering Cancer Center, New York, New York Weill Cornell Medical College, New York, New York
Cynthia Eisenstein
Affiliation:
Employee Health and Wellness Services, Memorial Sloan-Kettering Cancer Center, New York, New York
*
Employee Health and Wellness Services, Memorial Sloan-Kettering Cancer Center, 222 East 70th Street, New York, NY 10021 ([email protected])
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Abstract

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Type
Letters to the Editor
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

References

1. Gandra, S, Scott, WS, Somaraju, V, Wang, H, Wilton, S, Feigenbaum, M. Questionable effectiveness of the QuantiFERON test (Celles-tis) as a screening tool in healthcare workers. Infect Control Hosp Epidemiol 2010;31:12791285.Google Scholar
2. Gandra, S, Scott, WS, Somaraju, V. Reply to Joshi et al. Infect Control Hosp Epidemiol 2011;32:518519.Google Scholar
3. Joshi, M, Monson, T, Woods, G. Practical experience with the QFT-GIT assay for LTBI annual testing among US heath-care workers in a large tertiary setting. Chest 2010;138:746A.Google Scholar
4. Joshi, M, Monson, T, Woods, G. QuantiFERON-TB test for annual screening of healthcare workers: not yet ready for prime time in low-prevalence countries. Infect Control Hosp Epidemiol 2011;32:518.Google Scholar
5. Schneider, WJ, Eisenstein, C, Brown, AE, Patel, PH. Higher than expected annual QuantiFERON-Gold (QFT-G) “conversion” rate suggests a need for redefining reactivity criteria in healthcare workers (HCWs). 47th annual meeting of the Infectious Diseases Society of America, 29 October-1 November 2009; Philadelphia.Google Scholar
6. Schneider, WJ, Brown, AE, Eisenstein, C. Successive comparative observations of test results using QuantiFERON-Gold (QFT-G) and QuantiFERON-Gold In Tube (QFT-GIT): implications in a health worker setting. 48th annual meeting of the Infectious Diseases Society of America, 23 October 2010; Vancouver. Abstract 4947; poster LB-24.Google Scholar
7. Brown, AE, Eisenstein, C, Schneider, WJ, Kiehn, TE, Glickman, M. Results of QuantiFERON-TB Gold (QFT-G) testing of employees in a healthcare setting. 45th annual meeting of the Infectious Diseases Society of America, 4-7 October 2007; San Diego, CA. Abstract LB-12.Google Scholar
8. Harada, N, Higuchi, K, Yoshiyama, T, et al. Comparison of the sensitivity and specificity of two whole blood interferon-gamma assays for M. tuberculosis infection . J Infect 2008;56:348353.Google Scholar