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Pseudomonas aeruginosa Infections Associated with Use of Povidone-Iodine in Patients Receiving Continuous Ambulatory Peritoneal Dialysis

Published online by Cambridge University Press:  21 June 2016

Angella Goetz  and
Robert R. Muder
Angella Goetz
Affiliation:
Departments of Medicine, Veterans Administration Medical Center, Pittsburgh, Pennsylvania
Robert R. Muder*
Affiliation:
Departments of Medicine, Veterans Administration Medical Center, Pittsburgh, Pennsylvania Mercy Hospital of Pittsburgh, Pittsburgh, Pennsylvania
*
Infectious Disease Section, VA Medical Center, University Drive C, Pittsburgh, PA 15240
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Abstract

Fifteen episodes of infection due to Pseudomonas aeruginosa, including peritonitis and catheter site infections, occurred in nine patients receiving continuous ambulatory peritoneal dialysis over a 27-month period. Eight episodes were associated with catheter loss. Occurrence of P aeruginosa infection was significantly associated with use of povidone-iodine solution to cleanse the catheter site. There was no association with use of povidone-iodine solution to disinfect tubing connections, use of other skin care products or exposure to other environmental sources of P aeruginosa. Cultures of available povidone-iodine products were negative. Local irritation and alteration in skin flora caused by antiseptic solution or low-level contamination of povidone-iodine solution are potential mechanisms of infection.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 10 , Issue 10 , October 1989 , pp. 447 - 450
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1989

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