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Pokes, Pathogens, and Primum Non Nocere: Prudent Prophylaxis Protocols for Prostate Biopsy

Published online by Cambridge University Press:  02 January 2015

Sarah M. Drawz  and
James R. Johnson
Sarah M. Drawz*
Affiliation:
University of Minnesota, Minneapolis, Minnesota
James R. Johnson
Affiliation:
University of Minnesota, Minneapolis, Minnesota Veterans Affairs Medical Center, Minneapolis, Minnesota
*
Department of Lab Medicine and Pathology, MMC 609, 420 Delaware Street SE, Minneapolis, MN 55455 ([email protected])
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Extract

Infectious complications following transrectal ultrasound-guided biopsy of the prostate (TRUBP)—including urinary tract infections, prostatitis, epididymo-orchitis, and bacteremia—have increased dramatically in recent years. Traditionally, fluoroquinolones have been the mainstay for perioperative prophylaxis. Likely as a result of a combination of this selective pressure and temporal shifts in the clonal composition of the rectal microbiota, most post-TRUBP infections today are caused by fluoroquinolone-resistant Escherichia coli, especially those from sequence type 131 (ST131), an emerging multidrug-resistant strain that is highly prevalent among pre-TRUBP rectal isolates. Clinicians need improved approaches for preventing these complications. Fortunately, helpful guidance is beginning to appear.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 9 , September 2013 , pp. 977 - 979
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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