Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-16T21:18:05.180Z Has data issue: false hasContentIssue false
  • English
  • Français

Outbreak of Colonization and Infection With Vancomycin-Resistant Enterococcus faecium in a French University Hospital

Part of: BARRY FARR AWARD RECIPIENTS

Published online by Cambridge University Press:  21 June 2016

Olivier Lesens ,
L. Mihaila ,
F. Robin ,
O. Baud ,
J. P. Romaszko ,
O Tourniac ,
J. M. Constantin ,
B. Souweine ,
R. Bonnet  and
A. Bouvet
...Show all authors
Olivier Lesens*
Affiliation:
Service des Maladies Infectieuses et Tropicales, Hôtel-Dieu, France
L. Mihaila
Affiliation:
Service de Réanimation Médicale, Hôpital Gabriel-Montpied, France
F. Robin
Affiliation:
Service de Bactériologie, CHU de Clermont-Ferrand, France
O. Baud
Affiliation:
Service d'Hygiène Hospitalière, Faculté de Médecine de Clermont-Ferrrand, France
J. P. Romaszko
Affiliation:
Service de Bactériologie, CHU de Clermont-Ferrand, France
O Tourniac
Affiliation:
Service d'Hématologie Clinique, Hôtel-Dieu, France
J. M. Constantin
Affiliation:
Service de Réanimation Médico–chirurgicale, Hôtel-Dieu, France
R. Bonnet
Affiliation:
Service de Bactériologie, CHU de Clermont-Ferrand, France
A. Bouvet
Affiliation:
Clermont-Ferrand, and the Centre National de Référence des Streptocoques, Service de Microbiologie, Hôtel-Dieu, Assistance Publique-Hôpitaux de Paris, Université Paris V, Paris, France
J. Beytout
Affiliation:
Service des Maladies Infectieuses et Tropicales, Hôtel-Dieu, France
O. Traore
Affiliation:
Clermont-Ferrand, and the Centre National de Référence des Streptocoques, Service de Microbiologie, Hôtel-Dieu, Assistance Publique-Hôpitaux de Paris, Université Paris V, Paris, France
H. Laurichesse
Affiliation:
Service des Maladies Infectieuses et Tropicales, Hôtel-Dieu, France
*
Service des Maladies Infectieuses et Tropicales, Hôtel-Dieu, CHU, 63000 Clermont-Ferrand, France, ([email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

An outbreak of infection with vancomycin-resistant Enterococcus faecium occurred at Hôtel-Dieu Hospital (Clermont-Ferrand, France). A case-control study was performed in the infectious diseases and hematology units of the hospital. Urinary catheter use (odds ratio [OR], 12 [95% confidence interval {CI}, 1.5-90]; P<.02), prior exposure to a third-generation cephalosporin (OR, 22 [95% CI, 3-152]; P = .002), and prior exposure to antianaerobials (OR, 11 [95% CI, 1.5-88]; P<.02) were independently predictive of vancomycin-resistant Enterococcus faecium carriage.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 27 , Issue 9 , September 2006 , pp. 984 - 986
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Members of the SFM Antibiogram Committee. Comite de l'Antibiogramme de la Societe Francaise de Microbiologie report 2003. Int J Antimicrob Agents 2003; 21:364–391.Google Scholar
2.Dutka-Malen, S, Evers, S, Courvalin, P. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J Clin Microbiol 1995; 33:1434.CrossRefGoogle Scholar
3.Harris, AD, Karchmer, TB, Carmeli, Y, Samore, MH. Methodological principles of case control studies that analyzed risk factors for antibiotic resistance: a systematic review. Clin Infect Dis 2001; 32:1055–1061.CrossRefGoogle ScholarPubMed
4.Rice, LB, Hutton-Thomas, R, Lakticova, V, Helfand, MS, Donskey, CJ. Beta-lactam antibiotics and gastrointestinal colonization with vancomycin-resistant enterococci. J Infect Dis 2004; 189:1113–1118.Google Scholar
5.Lesens, O, Méthlin, C, Hansmann, Y, et al. Role of comorbidity in mortality related to Staphylococcus aureus bacteremia: a prospective study using the Charlson Weighted Index of Comorbidity. Infect Control Hosp Epidemiol 2003; 24:890–896.CrossRefGoogle ScholarPubMed
6.Boisivon, A, Thibault, M, Leclercq, R. Colonization by vancomycin-resistant enterococci of the intestinal tract of patients in intensive care units from French general hospitals. Clin Microbiol Infect 1997; 3:175–179.CrossRefGoogle ScholarPubMed
7.Schouten, MA, Hoogkamp-Korstanje, JA, Meis, JF, Voss, A. Prevalence of vancomycin-resistant enterococci in Europe. European VRE Study Group. Eur J Clin Microbiol Infect Dis 2000; 19:816–822.Google Scholar
8.Bingen, EH, Denamur, E, Lambert-Zechovsky, NY, Elion, J. Evidence for the genetic unrelatedness of nosocomial vancomycin-resistant Enterococcus faecium strains in a pediatric hospital. j Clin Microbiol 1991; 29:1888–1892.CrossRefGoogle Scholar
9.Gambarotto, K, Ploy, MC, Turlure, P, et al. Prevalence of vancomycin-resistant enterococci in fecal samples from hospitalized patients and non-hospitalized controls in a cattle-rearing area of France. J Clin Microbiol 2000; 38:620–624.CrossRefGoogle Scholar
10.Leavis, HL, Willems, RJ, Top, J, et al. Epidemic and nonepidemic multidrug-resistant Enterococcus faecium. Emerg Infect Dis 2003; 9:1108–1115.CrossRefGoogle ScholarPubMed