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MRSA prevalence and hospital-level antibiotic use: A retrospective study across 122 acute-care hospitals

Published online by Cambridge University Press:  17 September 2020

Daniel J. Livorsi Open the ORCID record for Daniel J. Livorsi [Opens in a new window] ,
Rajeshwari Nair ,
Brian C. Lund ,
Bruce Alexander ,
Brice F. Beck ,
Michihiko Goto  and
Eli N. Perencevich
Daniel J. Livorsi*
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA
Rajeshwari Nair
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA
Brian C. Lund
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA
Bruce Alexander
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA
Brice F. Beck
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA
Michihiko Goto
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA
Eli N. Perencevich
Affiliation:
Center for Access & Delivery Research & Evaluation (CADRE), Iowa City Veterans’ Affairs Health Care System, Iowa City, IA, USA Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA
*
Author for correspondence: Daniel Livorsi, E-mail: [email protected]
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Abstract

We evaluated the relationship between local MRSA prevalence rates and antibiotic use across 122 VHA hospitals in 2016. Higher hospital-level MRSA prevalence was associated with significantly higher rates of antibiotic use, even after adjusting for case mix and stewardship strategies. Benchmarking anti-MRSA antibiotic use may need to adjust for MRSA prevalence.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 42 , Issue 3 , March 2021 , pp. 353 - 355
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Copyright
© 2020 by The Society for Healthcare Epidemiology of America. All rights reserved.

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References

Barlam, TF, Cosgrove, SE, Abbo, LM, et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 2016;62:e51–e77.CrossRefGoogle Scholar
Jain, R, Kralovic, SM, Evans, ME, et al. Veterans’ Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections. N Engl J Med 2011;364:1419–1430.CrossRefGoogle Scholar
Antimicrobial use and resistance module. Centers for Disease Control and Prevention website. https://www.cdc.gov/nhsn/pdfs/pscmanual/11pscaurcurrent.pdf. Published 2020. Accessed May 20, 2020.Google Scholar
Morris, AM, Calderwood, MS, Fridkin, SK, et al. Research needs in antibiotic stewardship. Infect Control Hosp Epidemiol 2019;40:1334–1343.CrossRefGoogle ScholarPubMed
Parente, DM, Cunha, CB, Mylonakis, E, Timbrook, TT. The clinical utility of methicillin-resistant Staphylococcus aureus (MRSA) nasal screening to rule out MRSA pneumonia: a diagnostic meta-analysis with antimicrobial stewardship implications. Clin Infect Dis 2018;67:1–7.CrossRefGoogle ScholarPubMed
Mergenhagen, KA, Starr, KE, Wattengel, BA, Lesse, AJ, Sumon, Z, Sellick, JA. Determining the utility of methicillin-resistant Staphylococcus aureus nares screening in antimicrobial stewardship. Clin Infect Dis 2020;71:1142–1148.CrossRefGoogle ScholarPubMed
Jones, BE, Brown, KA, Jones, MM, et al. Variation in empiric coverage versus detection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in hospitalizations for community-onset pneumonia across 128 US Veterans’ Affairs Medical Centers. Infect Control Hosp Epidemiol 2017;38:937–944.CrossRefGoogle Scholar
Nelson, RE, Evans, ME, Simbartl, L, et al. Methicillin-resistant Staphylococcus aureus colonization and pre– and post–hospital discharge infection risk. Clin Infect Dis 2019;68:545–553.CrossRefGoogle ScholarPubMed
Stone, ND, Lewis, DR, Johnson, TM, 2nd, et al. Methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage in residents of Veterans’ Affairs long-term care facilities: role of antimicrobial exposure and MRSA acquisition. Infect Control Hosp Epidemiol 2012;33:551–557.CrossRefGoogle Scholar
Couderc, C, Jolivet, S, Thiebaut, AC, et al. Fluoroquinolone use is a risk factor for methicillin-resistant Staphylococcus aureus acquisition in long-term care facilities: a nested case–case-control study. Clin Infect Dis 2014;59:206–215.CrossRefGoogle ScholarPubMed
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