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Methicillin-Resistant Staphylococcus aureus Decolonization “Yes, We Can,” But Will It Help?

Published online by Cambridge University Press:  02 January 2015

Jan Kluytmans  and
Stephan Harbarth
Jan Kluytmans*
Affiliation:
Department of Medical Microbiology and Infectious Diseases, University Medical Center, Amsterdam Laboratory for Microbiology and Infection Control, Amphia Hospital, Breda
Stephan Harbarth
Affiliation:
The Netherlands; and the Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
*
Laboratory for Microbiology and Infection Control, Amphia Hospital Breda, PO Box 90158, 4800 RK Breda, The Netherlands ([email protected])
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Abstract

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Type
Editorial
Information
Infection Control & Hospital Epidemiology , Volume 30 , Issue 7 , July 2009 , pp. 633 - 635
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

References

1.Klevens, RM, Morrison, MA, Nadle, J, et al. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 2007;298:1763–1771.Google Scholar
2.Kluytmans-VandenBergh, MF, Kluytmans, JA. Community-acquired methicillin-resistant Staphylococcus aureus: current perspectives. Clin Microbiol Infect 2006;12(Suppl 1):9–15.Google Scholar
3.Atkins, JB, Marks, J. The role of staphylococcal infection in beat disorders of miners. Brit J Ind Med 1952;9:296–302.Google Scholar
4.Kluytmans, J, van Belkum, A, Verbrugh, H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997;10:505–520.CrossRefGoogle ScholarPubMed
5.van Rijen, M, Bonten, M, Wenzel, R, Kluytmans, J. Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers. Cochrane Database Syst Rev 2008;4:CD006216.Google Scholar
6.Tacconelli, E, Carmeli, Y, Aizer, A, Ferreira, G, Foreman, MG, D’Agata EM. Mupirocin prophylaxis to prevent Staphylococcus aureus infection in patients undergoing dialysis: a meta-analysis. Clin Infect Dis 2003;37:1629–1638.Google Scholar
7.Bode, LG, Kluytmans, JA, Wertheim, HF, et al. A randomized trial of admission screening and decolonization of Staphyiococcus aureus carriers to prevent nosocomial S. aureus infections. In: Proceedings of the 48th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, DC: American Society for Microbiology; 2008:25–28. Abstract K-1711.Google Scholar
8.Harbarth, S, Liassine, N, Dharan, S, Herrault, P, Auckenthaler, R, Pittet, D. Risk factors for persistent carriage of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2000;31:1380–1385.Google Scholar
9.Simor, AE, Phillips, E, McGeer, A, et al. Randomized controlled trial of Chlorhexidine gluconate for washing, intranasal mupirocin, and rifampin and doxycycline versus no treatment for the eradication of methicillin-resistant Staphylococcus aureus colonization. Clin Infect Dis 2007;44:178–185.CrossRefGoogle ScholarPubMed
10.Harbarth, S, Fankhauser, C, Schrenzel, J, et al. Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. JAMA 2008;299:1149–1157.CrossRefGoogle ScholarPubMed
11.Ammerlaan, HS, Kluytmans, JA, Wertheim, HF, Nouwen, JL, Bonten, MJ. Eradication of methicillin-resistant Staphylococcus aureus carriage: a systematic review. Clin Infect Dis 2009;48:922–930.Google Scholar
12.Buehlmann, M, Frei, R, Fenner, L, Dangel, M, Fluckiger, U, Widmer, AF. Highly effective regimen for decolonization of methicillin-resistant Staphylococcus aureus carriers. Infect Control Hosp Epidemiol 2008;29:510–516.Google Scholar
13.Rohr, U, Mueller, C, Wilhelm, M, Muhr, G, Gatermann, S. Methicillin-resistant Staphylococcus aureus whole-body decolonization among hospitalized patients with variable site colonization by using mupirocin in combination with octenidine dihydrochloride. J Hosp Infect 2003;54:305–309.Google Scholar
14.Robicsek, A, Beaumont, JL, Paule, SM, et al. Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med 2008;148:409–418.Google Scholar
15.Chaberny, IF, Schwab, F, Ziesing, S, Suerbaum, S, Gastmeier, P. Impact of routine surgical ward and intensive care unit admission surveillance cultures on hospital-wide nosocomial methicillin-resistant Staphylococcus aureus infections in a university hospital: an interrupted time-series analysis. J Antimicrob Chemother 2008;62:1422–1429.Google Scholar
16.Robicsek, A, Beaumont, JL, Thomson, RB Jr, Govindarajan, G, Peterson, LR. Topical therapy for methicillin-resistant Staphylococcus aureus colonization: impact on infection risk. Infect Control Hosp Epidemiol 2009;30: 623–632 (in this issue).Google Scholar
17.Wertheim, HF, Vos, MC, Ott, A, et al. Mupirocin prophylaxis against nosocomial Staphylococcus aureus infections in nonsurgical patients: a randomized study. Ann Intern Med 2004;140:419–425.Google Scholar
18.Bradley, SF. Eradication or decolonization of methicillin-resistant Staphylococcus aureus carriage: what are we doing and why are we doing it? Clin Infect Dis 2007;44:186–189.Google Scholar
19.Simor, AE, Daneman, N. Staphylococcus aureus decolonization as a prevention strategy. Infect Dis Clin North Am 2009;23:133–151.CrossRefGoogle ScholarPubMed
20.Mody, L, Kauffman, CA, McNeil, SA, Galecki, AT, Bradley, SF. Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis 2003;37:1467–1474.Google Scholar