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Managing Occupational Exposures to HIV-1 in the Healthcare Workplace

Published online by Cambridge University Press:  21 June 2016

Barbara J. Fahey
Affiliation:
Hospital Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda
Susan E. Beekmann
Affiliation:
Hospital Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda
James M. Schmitt
Affiliation:
Occupational Medical Service, Division of Safety, Clinical Center, National Institutes of Health, Bethesda
Joan M. Fedio
Affiliation:
Occupational Medical Service, Division of Safety, Clinical Center, National Institutes of Health, Bethesda
David K. Henderson*
Affiliation:
Hospital Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda Office of the Director, Clinical Center, National Institutes of Health, Bethesda
*
Warren G. Magnuson Clinical Center, National Institutes of Health, Building 10, Room 2C146, Bethesda, MD 20892

Extract

Managing occupational exposures to human immunodeficiency virus type 1 (HIV-1) in the healthcare workplace remains both controversial and complex. Healthcare workers' perceptions of risk for occupational transmission of HIV-1, their knowledge of risk-reduction strategies, and their perceptions about appropriate postexposure management are all derived from an intricate interplay of scientific, political, social, and emotional sources. Following an occupational exposure to blood or blood-containing body fluids, a healthcare worker's immediate emotional response may be extreme gut-wrenching anxiety, with perceptions often biased by ignorance, uncertainty, and fear. The healthcare worker's postinjury emotional and psychological stress can be extraordinary; postinjury therapy, of necessity, must integrate medical, physical, psychological, and psychosocial aspects of care. Clinical decisions regarding HIV-1 injury management, therefore, are based not only on available scientific and medical information but also on measured actions designed to manage and presumably to diminish the profound anxiety almost invariably associated with an occupational exposure to HIV-1. In stark contrast to this common and extreme emotional reaction, the likelihood of disease transmission from such occupational exposures is relatively small.

In this article, we will discuss a series of questions and issues typically encountered when a healthcare worker sustains an occupational exposure to HIV-1.

Type
AIDS
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1993

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References

1. Beekmann, SE, Fahey, BJ, Gerberding, JL, Henderson, DK. Risky business: using necessarily imprecise casualty counts to estimate occupational risks for HIV-1 infection. Infect Control Hasp Epidemiol 1990;11:371379.CrossRefGoogle ScholarPubMed
2. Centers for Disease Control. Summary: recommendations for preventing transmission of infection with human Tlymphotropic virus type III/lymphadenopathy-associated virus in the workplace. MMWR 1985;34:681695.Google Scholar
3. Henderson, DK. HIV-1 in the health care setting. In: Mandell, GL, Douglas, RG Jr Bennett, JE, eds. Principles and Practice of Infectious Diseases. 4th ed. New York, NY: Livingstone. In press.Google Scholar
4. Fahey, BJ, Koziol, DE, Banks, SM, Henderson, DK. Frequency of nonparenteral occupational exposures to blood and body fluids before and after universal precautions training. Am J Med 1991;90:145153.CrossRefGoogle ScholarPubMed
5. Gerberding, JL, Henderson, DK. Management of occupational exposures to bloodbome pathogens: hepatitis B virus, hepatitis C virus, and human immunodeficiency virus. Clin Infect Dis 1992;14:11791185.CrossRefGoogle Scholar
6. Woolwine, J, Mast, S, Gerberding, JL. Factors influencing needlestick infectivity and decontamination efficacy: an ex vivo model. In: Program and Abstracts 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy. Anaheim, California: American Society for Microbiology; 1992. Abstract 1188.Google Scholar
7. Beekmann, SE, Henderson, DK. Health care workers and hepatitis: risk for infection and management of exposures. Infect Dis Clin Pract 1992;1:424428.Google Scholar
8. Henderson, DK. Postexposure chemoprophylaxis for occupational exposure to human immunodeficiency virus type 1: current status and prospects for the future. Am J Med 1991;91(suppl 3B):312S319S.CrossRefGoogle ScholarPubMed
9. Henderson, DK, Gerberding, JL. Prophylactic zidovudine after occupational exposure to the human immunodeficiencyvirus: an interim analysis. J Infect Dis 1989;160:321327.CrossRefGoogle Scholar
10. Jaffe, HA, Schmitt, J. AIDS in the workplace. In: Rom, WN, ed. Environmental and Occupational Medicine. 2nd ed. Boston, MA: Little, Brown and Co.; 1992:685713.Google Scholar