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Low Frequency of Endemic Patient-to-Patient Transmission of Antibiotic-Resistant Gram-Negative Bacilli in a Pediatric Intensive Care Unit

Published online by Cambridge University Press:  02 January 2015

Joan Zoltanski*
Affiliation:
Division of Pharmacology and Critical Care, Rainbow Babies and Children’s Hospital, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio
Michael Dul
Affiliation:
Division of Pharmacology and Critical Care, Rainbow Babies and Children’s Hospital, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio
Mary Ann O’Riordan
Affiliation:
Division of Pharmacology and Critical Care, Rainbow Babies and Children’s Hospital, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio
Jeffrey Blumer
Affiliation:
Division of Pharmacology and Critical Care, Rainbow Babies and Children’s Hospital, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio
Philip Toltzis
Affiliation:
Division of Pharmacology and Critical Care, Rainbow Babies and Children’s Hospital, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio
*
Rainbow Babies and Children's Hospital 11100 Euclid Avenue, Cleveland, OH 44106 ([email protected])

Extract

We sought to determine the frequency of horizontal transmission of antibiotic-resistant gram-negative bacilli (ARGNB) in a pediatric intensive care unit during a nonoutbreak period. Among 5,300 admissions over 39 consecutive months, 13 ARGNB clusters involving 35 children were identified by pulsed-filed gel electrophoresis analysis, which suggests that person-to-person transmission was uncommon.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

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