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Large Outbreak of Infection and Colonization with Gram-Negative Pathogens Carrying the Metallo-β-Lactamase Gene blaIMP-4 at a 320-Bed Tertiary Hospital in Australia

Published online by Cambridge University Press:  02 January 2015

Sophie Herbert
Affiliation:
Infectious Diseases and Microbiology Department, The Alfred Hospital, Melbourne, Victoria, Australia
Dag S. Halvorsen
Affiliation:
Infectious Diseases and Microbiology Department, The Alfred Hospital, Melbourne, Victoria, Australia
Tim Leong
Affiliation:
Intensive Care Unit, The Alfred Hospital, Melbourne, Victoria, Australia
Clare Franklin
Affiliation:
Infectious Diseases and Microbiology Department, The Alfred Hospital, Melbourne, Victoria, Australia
Glenys Harrington
Affiliation:
Infection Control and Epidemiology Unit, The Alfred Hospital, Melbourne, Victoria, Australia
Denis Spelman*
Affiliation:
Infectious Diseases and Microbiology Department, The Alfred Hospital, Melbourne, Victoria, Australia
*
Infectious Diseases and Microbiology Department, The Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia, ([email protected])

Abstract

A large outbreak of infection and colonization with multiple genera of gram-negative bacilli carrying the metallo-β-lactamase gene blaIMP-4 occurred in a 36-bed intensive care unit at a tertiary hospital in Australia. The organisms emerged rapidly, caused severe infections, and contributed to mortality. Controlling the spread of these organisms remains a challenge for all staff involved.

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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