Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-22T22:39:51.011Z Has data issue: false hasContentIssue false

Klebsiella pneumoniae Carbapenemase–Producing Organisms: An Ounce of Prevention Really Is Worth a Pound of Cure

Published online by Cambridge University Press:  02 January 2015

Arjun Srinivasan*
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
Jean B. Patel
Affiliation:
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
*
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd., MS A35, Atlanta, GA 30333 ([email protected])

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Commentary
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Yigit, H., Queenan, AM, Andersen, GJ, et al. Novel carbapenem-hydrolyzing β-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae . Antimicrob Agents Chemother 2001;45:11511161.CrossRefGoogle ScholarPubMed
2. Queenan, AM, Bush, K. Carbapenemases: the versatile β-lactamases. Clin Microbiol Rev 2007;20:440458.Google ScholarPubMed
3. Rice, LB, Carias, LL, Hutton, RA, Rudin, SD, Endimiani, A, Bonomo, RA. The KQ element, a complex genetic region conferring transferable resistance to carbapenems, aminoglycosides, and fluoroquinolones in Klebsiella pneumoniae . Antimicrob Agents Chemother 2008;52:34273429.CrossRefGoogle ScholarPubMed
4. Patel, G, Huprikar, S, Factor, SH, Jenkins, SG, Calfee, DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008;29:10991106 (in this issue).CrossRefGoogle ScholarPubMed
5. Lee, K, Chong, Y, Shin, HB, Kim, YA, Yong, D, Yum, JH. Modified Hodge and EDTA-disk synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect 2001;7:8891.CrossRefGoogle ScholarPubMed
6. Leavitt, A, Navon-Venezia, S, Chmelnitsky, I, Schwaber, MJ, Carmeli, Y. Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. Antimicrob Agents Chemother 2007;51:30263029.CrossRefGoogle Scholar
7. Samra, Z, Ofir, O, Lishtzinsky, Y, Mador-Shapiro, L, Bishara, J. Outbreak of carbapenem-resistant Klebsiella pneumoniae producing KPC-3 in a tertiary medical centre in Israel. Int J Antimicrob Agents 2007;30:525529.CrossRefGoogle Scholar
8. Stürenburg, E, Mack, D. Extended-spectrum β-lactamases: implications for the clinical microbiology laboratory, therapy, and infection control. J Infect 2003;47:273295.Google ScholarPubMed
9. Management of Multi-Drug Resistant Organisms in Healthcare Settings, 2006. Healthcare Infection Control Practices Advisory Committee. Available at: http://www.cdc.gov/ncidod/dhqp/pdf/ar/mdroGuideline2006.pdf. Accessed October 17, 2008.Google Scholar