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Influence of Ethanol With and Without Chlorhexidine on the Bacterial Colonization of the Umbilicus of Newborn Infants

Published online by Cambridge University Press:  02 January 2015

S. Bygdeman ,
A Hambraeus ,
A. Henningsson ,
B. Nyström ,
C. Skoglund  and
R. Tunell
S. Bygdeman*
Affiliation:
Departments of Clinical Microbiology, Obstetrics and Gynecology and Pediatrics, Huddinge University Hospital, Uppsala, Sweden Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden
A Hambraeus
Affiliation:
Departments of Clinical Microbiology, Obstetrics and Gynecology and Pediatrics, Huddinge University Hospital, Uppsala, Sweden Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden
A. Henningsson
Affiliation:
Departments of Clinical Microbiology, Obstetrics and Gynecology and Pediatrics, Huddinge University Hospital, Uppsala, Sweden Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden
B. Nyström
Affiliation:
Departments of Clinical Microbiology, Obstetrics and Gynecology and Pediatrics, Huddinge University Hospital, Uppsala, Sweden Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden
C. Skoglund
Affiliation:
Departments of Clinical Microbiology, Obstetrics and Gynecology and Pediatrics, Huddinge University Hospital, Uppsala, Sweden Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden
R. Tunell
Affiliation:
Departments of Clinical Microbiology, Obstetrics and Gynecology and Pediatrics, Huddinge University Hospital, Uppsala, Sweden Institute of Clinical Bacteriology, University of Uppsala, Uppsala, Sweden
*
Dept. of Clinical Microbiology, Huddinge University Hospital, S 141 86 Huddinge, Sweden
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Abstract

The effect of daily treatments with 70% ethanol and with 0.5% Chlorhexidine in 70% ethanol, respectively, on navel colonization in newborns has been studied in 624 infants in two maternity wards during a four-month period. Staphylococcus aureus, group B and G streptococci, E. coli and anaerobes were significantly less often isolated from newborns whose umbilical cord was treated with Chlorhexidine in ethanol than from those treated with ethanol only. Staphylococcus epidermidis and enterococci, on the other hand, were significantly more often isolated from the chlorhexidine-ethanol than from the ethanol group. More infants without colonization of the umbilicus on their fourth day of life were found in the Chlorhexidine in ethanol than in the ethanol group. The infants in the ethanol group were colonized with significantly more bacterial species than the infants in the other group. Signs of dissemination of group B and group G streptococci between babies were seen more often in the group of infants treated with ethanol than in the one treated with chlorhexidine-ethanol.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 5 , Issue 6 , June 1984 , pp. 275 - 278
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1984

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References

1.Bennet, R, Eriksson, M, Zetterström, R, Increasing incidence of neonatal septicemia: Causative organisms and predisposing risk factors. Acta Paediatr Scand 1981;70:207–210.CrossRefGoogle ScholarPubMed
2.Freedman, RM, Ingram, DL, Gross, I, et al: A half century of neonatal sepsis at Yale. Am J Dis Child 1981;135:140–144.CrossRefGoogle ScholarPubMed
3.Wilson, HD, Eichenwald, HF, Sepsis neonatorum. Pediatr Clin North Am 1974;21:571–582.CrossRefGoogle ScholarPubMed
4.Mortimer, EA, Wolinsky, E, Gonzaga, AJ, et al: Role of airborne transmission in staphylococcal infections. Br Med J 1966;1:319–322.CrossRefGoogle ScholarPubMed
5.Berg, U, Bygdeman, S, Henningsson, A, et al: An outbreak of group A streptococcal infections in a maternity unit. Journal of Hospital Infections, to be published.Google Scholar
6.Bygdeman, S, Jacobsson, E, Myrbäck, K-E, et al: Hemolytic streptococci among infants in a maternity department. Scand J Infect Dis 1978;10:45–49.CrossRefGoogle Scholar
7.Speck, WT, Driscoll, JM, Polin, RA, et al: Effect of bacterial flora on staphylococcal colonization of the newborn. J Clin Pathol 1978;31:153–155.CrossRefGoogle ScholarPubMed
8.Lowbury, EJL, Lilly, HA, Ayliffe, GAJ, Preoperative disinfection of surgeons' hands: Use of alcoholic solutions and effects of gloves on skin flora. Br Med J 1974;704:369–372.CrossRefGoogle Scholar
9.Rotter, ML, Povidone-iodine and Chlorhexidine gluconate containing detergents for disinfection of hands. Journal of Hospital Infections 1981;2:273–280.CrossRefGoogle ScholarPubMed
10.Henningsson, A, Nyström, B, Tunell, R, Bathing or washing babies after birth? Lancet 1981;19:1401–1403.CrossRefGoogle Scholar
11.Cunningham, L, Catlin, W, Privat de Garilhe, M, A deox-yribonuclease of Micrococcus pyogenes. The Journal of the American Chemical Society. 1956;78:4642–4645.CrossRefGoogle Scholar
12.DiSalvo, J, Desoxyribonuclease and coagulase activity of micrococci. Medical Technicians Bulletin, 1958;9:191–196.Google ScholarPubMed
13.Stringer, J, The development of a phage typing system for group B streptococci. J Med Microbiol 1980;13:133–143.CrossRefGoogle ScholarPubMed
14.Boissard, JM, Neonatal umbilicus as a source of streptococcal infections in a maternity unit. Br Med J 1956;2:574–576.CrossRefGoogle Scholar
15.Huntingford, PJ, Welch, G, Wetherley-Mein, G, Problem of the neonatal umbilicus and its relation to the incidence of sepsis in a maternity unit. Journal of Obstetrics and Gynecology 1961;68:179–182.Google Scholar
16.Easmon, CSF, Hastings, MJG, Clare, AJ, et al: Nosocomial transmission of group B streptococci. Br Med J 1981;282:459–461.CrossRefGoogle Scholar
17.Shinefield, HR, Ribble, JC, Eichenwald, HF, et al: Bacterial interference, in Maibach, HI, Hildick-Smith, G (eds): Skin Bacteria and Their Role in Infection. New York, McGraw-Hill, 1965, pp 235–251.Google Scholar
18.Wickman, K, Studies of bacterial interference in experimentally produced burns in guinea pigs. Acta Pathol Microbiol Scand [B] 1970;78:15–28.Google ScholarPubMed