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Impact of Vancomycin Minimum Inhibitory Concentration on Mortality among Critically Ill Patients witn Methicillin-Resistant Staphylococcus aureus Bacteremia

Published online by Cambridge University Press:  02 January 2015

Christian J. Woods
Affiliation:
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC Georgetown University, Washington, DC
Anindita Chowdhury
Affiliation:
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC
Vinay M. Patel
Affiliation:
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC
Andrew F. Shorr*
Affiliation:
Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC
*
Pulmonary and Critical Care Medicine, Room 2A-69D, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010 ([email protected])

Abstract

We retrospectively evaluated 99 intensive care unit patients with methicillin-resistant Staphylococcus aureus bacteremia to determine whether having a vancomycin minimum inhibitory concentration (MIC) of 2 mg/L affected mortality. This MIC was found in 5.1% of patients and was associated with the probability of death (adjusted odds ratio, 13.9 [95% confidence interval, 1.1–171.2]) independent of other factors.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2012

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