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Hospital-acquired infections among adult patients admitted for coronavirus disease 2019 (COVID-19)

Published online by Cambridge University Press:  13 April 2021

Leigh Smith*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine
Sara M. Karaba
Affiliation:
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine
George Jones
Affiliation:
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine
Robin K. Avery
Affiliation:
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine
Kathryn Dzintars
Affiliation:
Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, MD
Taylor Helsel
Affiliation:
Johns Hopkins Armstrong Institute for Patient Safety and Quality, Baltimore, Maryland
Sara E. Cosgrove
Affiliation:
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine
Valeria Fabre
Affiliation:
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine
*
Author for correspondence: Leigh Smith, E-mail: [email protected]

Abstract

In a multicenter cohort of 963 adults hospitalized due to coronavirus disease 2019 (COVID-19), 5% had a proven hospital-acquired infection (HAI) and 21% had a proven, probable, or possible HAI. Risk factors for proven or probable HAIs included intensive care unit admission, dexamethasone use, severe COVID-19, heart failure, and antibiotic exposure upon admission.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Garcia-Vidal, C, Sanjuan, G, Moreno-Garcia, E, et al. Incidence of coinfections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study. Clin Microbiol Infect 2021;27:8388.CrossRefGoogle ScholarPubMed
Langford, BJ, So, M, Raybardhan, S, et al. Bacterial coinfection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis. Clin Microbiol Infect 2020;26:16221629.CrossRefGoogle ScholarPubMed
PMAP: The Johns Hopkins Precision Medicine Analytics Platform. Johns Hopkins inHealth website. https://pm.jh.edu/. Accessed April 5, 2021.Google Scholar
WHO R&D Blueprint: novel coronavirus COVID-19 therapeutic trial synopsis. World Health Organization website. https://www.who.int/blueprint/priority-diseases/key-action/COVID-19_Treatment_Trial_Design_Master_Protocol_synopsis_Final_18022020.pdf. Published 2020. Accessed April 5, 2021.Google Scholar
Magill, SS, O’Leary, E, Janelle, SJ, et al. Changes in prevalence of health care–associated infections in US hospitals. N Engl J Med 2018;379:17321744.CrossRefGoogle Scholar
Stevens, MP, Doll, M, Pryor, R, Godbout, E, Cooper, K, Bearman, G. Impact of COVID-19 on traditional healthcare-associated infection prevention efforts. Infect Control Hosp Epidemiol 2020;41:946947.CrossRefGoogle ScholarPubMed
Vaughn, VM, Gandhi, T, Petty, LA, et al. Empiric antibacterial therapy and community-onset bacterial coinfection in patients hospitalized with COVID-19: a multihospital cohort study. Clin Infect Dis 2020. doi: 10.1093/cid/ciaa1239.CrossRefGoogle Scholar
Caillard, S, Anglicheau, D, Matignon, M, et al. An initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants. Kidney Int 2020;98:15491558.CrossRefGoogle ScholarPubMed
Alanio, A, Dellière, S, Fodil, S, Bretagne, S, Mégarbane, B. Prevalence of putative invasive pulmonary aspergillosis in critically ill patients with COVID-19. Lancet Respir Med 2020;8(6):e48e49.CrossRefGoogle ScholarPubMed
Bartoletti, M, Pascale, R, Cricca, M, et al. Epidemiology of invasive pulmonary aspergillosis among COVID-19 intubated patients: a prospective study. Clin Infect Dis 2020. doi: 10.1093/cid/ciaa1065.CrossRefGoogle Scholar
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