Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-06T10:59:54.719Z Has data issue: false hasContentIssue false

Fecal Carriage of Extended-Spectrum β-Lactamase–Producing Escherichia coli and Klebsiella pneumoniae in Patients and Asymptomatic Healthy Individuals

Published online by Cambridge University Press:  02 January 2015

Abdulrahman Abdulla Kader*
Affiliation:
Department of Clinical Microbiology, Almana General Hospital, Department of Clinical Microbiology, Dammam, Saudi Arabia
Angamuthu Kumar
Affiliation:
Department of Clinical Microbiology, Almana General Hospital, Department of Clinical Microbiology, Dammam, Saudi Arabia
Katapadi Ananthkrishna Kamath
Affiliation:
Department of Clinical Microbiology, Almana General Hospital, Department of Clinical Microbiology, Dammam, Saudi Arabia
*
Almana General Hospital, Department of Clinical Microbiology, PO Box 1364, Al-Khobar 31952, Saudi Arabia ([email protected])

Abstract

Fecal carriage of extended-spectrum β-lactamase (ESBL)-producing organisms was assessed in 272 inpatients, 162 outpatients, and 426 asymptomatic healthy individuals. Of 860 stool samples cultured, 152 (17.7%) yielded ESBL-producing organisms. Isolates were recovered from 71 (26.1%) of the inpatients, 25 (15.4%) of the outpatients, and 56 (13.1%) of the healthy individuals. These findings suggest that the community could be a reservoir of ESBL-producing organisms.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Moland, SE, Black, JA, Ourada, J, Reisbig, MD, Hanson, ND, Thomson, KS. Occurrence of newer β-lactamases in Klebsiella pneumoniae isolates from 24 US hospitals. Antimicrob Agents Chemother 2002;46:38373842.Google Scholar
2. Bou, G, Cartelle, M, Tomas, M, et al. Identification and broad dissemination of the CTX-M-14 β-lactamase-lactamase in different Escherichia coli strains in the northwest area of Spain. J Clin Microbiol 2002;40:40304036.Google Scholar
3. Kader, AA, Kumar, A. Extended-spectrum beta-lactamases in urinary isolates of Escherichia coli, Klebsiella pneumoniae and other gram-negative bacteria in a hospital in Eastern Province, Saudi Arabia. Saudi Med J 2005;26:956959.Google Scholar
4. National Committee for Clinical Laboratory Standards (NCCLS). Performance Standards for Antimicrobial Susceptibility Testing: 15th Informational Supplement. Wayne, PA: NCCLS; 2005:M100-S15.Google Scholar
5. Cowan, SF, Steel, KJ. Manual for Identification of Medical Bacteria. 3rd ed. Cambridge: Cambridge University Press, 1993:140143.Google Scholar
6. Jarlier, V, Nicolas, MH, Fournier, G, Philippon, A. ESBLs conferring transferable resistance to newer β-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis 1988;10:867878.Google Scholar
7. Daoud, Z, Moubareck, C, Hakime, N, Doucet-Populaire, F. Extended spectrum β- lactamase producing Enterobacteriaceae in Lebanese ICU patients: epidemiology and patterns of resistance. J Gen Appl Microbiol 2006;52:169178.Google Scholar
8. Bosi, C, Davin-Regli, A, Bornet, C, Mallea, M, Pages, JM, Bollet, C. Most Enterobacter aerogenes strains in France belong to a prevalent clone. J Clin Microbiol 1999;37:21652169.Google Scholar
9. Colodner, R, Rock, W, Chazan, B, Keller, N, Sakran, W, Raz, R. Risk factors for the development of extended-spectrum β-lactamase producing bacteria in nonhospitalized patients. Eur J Clin Microbiol Infect Dis 2004;23:163167.Google Scholar
10. Lucet, JC, Chevret, S, Deere, DI. Outbreak of multiply resistant Enterobacteriaceae in an intensive care unit epidemiology and risk factors for acquisition. Clin Infect Dis 1996;22:430436.Google Scholar