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Fecal Carriage of Extended-Spectrum β-Lactamase–Producing Escherichia coli and Klebsiella pneumoniae in Patients and Asymptomatic Healthy Individuals

Published online by Cambridge University Press:  02 January 2015

Abdulrahman Abdulla Kader*
Affiliation:
Department of Clinical Microbiology, Almana General Hospital, Department of Clinical Microbiology, Dammam, Saudi Arabia
Angamuthu Kumar
Affiliation:
Department of Clinical Microbiology, Almana General Hospital, Department of Clinical Microbiology, Dammam, Saudi Arabia
Katapadi Ananthkrishna Kamath
Affiliation:
Department of Clinical Microbiology, Almana General Hospital, Department of Clinical Microbiology, Dammam, Saudi Arabia
*
Almana General Hospital, Department of Clinical Microbiology, PO Box 1364, Al-Khobar 31952, Saudi Arabia ([email protected])

Abstract

Fecal carriage of extended-spectrum β-lactamase (ESBL)-producing organisms was assessed in 272 inpatients, 162 outpatients, and 426 asymptomatic healthy individuals. Of 860 stool samples cultured, 152 (17.7%) yielded ESBL-producing organisms. Isolates were recovered from 71 (26.1%) of the inpatients, 25 (15.4%) of the outpatients, and 56 (13.1%) of the healthy individuals. These findings suggest that the community could be a reservoir of ESBL-producing organisms.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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References

1. Moland, SE, Black, JA, Ourada, J, Reisbig, MD, Hanson, ND, Thomson, KS. Occurrence of newer β-lactamases in Klebsiella pneumoniae isolates from 24 US hospitals. Antimicrob Agents Chemother 2002;46:38373842.Google Scholar
2. Bou, G, Cartelle, M, Tomas, M, et al. Identification and broad dissemination of the CTX-M-14 β-lactamase-lactamase in different Escherichia coli strains in the northwest area of Spain. J Clin Microbiol 2002;40:40304036.Google Scholar
3. Kader, AA, Kumar, A. Extended-spectrum beta-lactamases in urinary isolates of Escherichia coli, Klebsiella pneumoniae and other gram-negative bacteria in a hospital in Eastern Province, Saudi Arabia. Saudi Med J 2005;26:956959.Google Scholar
4. National Committee for Clinical Laboratory Standards (NCCLS). Performance Standards for Antimicrobial Susceptibility Testing: 15th Informational Supplement. Wayne, PA: NCCLS; 2005:M100-S15.Google Scholar
5. Cowan, SF, Steel, KJ. Manual for Identification of Medical Bacteria. 3rd ed. Cambridge: Cambridge University Press, 1993:140143.Google Scholar
6. Jarlier, V, Nicolas, MH, Fournier, G, Philippon, A. ESBLs conferring transferable resistance to newer β-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis 1988;10:867878.Google Scholar
7. Daoud, Z, Moubareck, C, Hakime, N, Doucet-Populaire, F. Extended spectrum β- lactamase producing Enterobacteriaceae in Lebanese ICU patients: epidemiology and patterns of resistance. J Gen Appl Microbiol 2006;52:169178.Google Scholar
8. Bosi, C, Davin-Regli, A, Bornet, C, Mallea, M, Pages, JM, Bollet, C. Most Enterobacter aerogenes strains in France belong to a prevalent clone. J Clin Microbiol 1999;37:21652169.Google Scholar
9. Colodner, R, Rock, W, Chazan, B, Keller, N, Sakran, W, Raz, R. Risk factors for the development of extended-spectrum β-lactamase producing bacteria in nonhospitalized patients. Eur J Clin Microbiol Infect Dis 2004;23:163167.Google Scholar
10. Lucet, JC, Chevret, S, Deere, DI. Outbreak of multiply resistant Enterobacteriaceae in an intensive care unit epidemiology and risk factors for acquisition. Clin Infect Dis 1996;22:430436.Google Scholar