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Experience with voluntary severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing of asymptomatic staff at the National Institutes of Health for one year

Part of: SARS-CoV-2/COVID-19

Published online by Cambridge University Press:  02 November 2021

Arthur H. Totten Open the ORCID record for Arthur H. Totten [Opens in a new window] ,
Ann Marie Matlock ,
Heike Bailin ,
Josanne Revoir ,
Christopher M. Siwy ,
Maria Joyce ,
Patricia Coffey Open the ORCID record for Patricia Coffey [Opens in a new window] ,
David K. Henderson ,
Tara N. Palmore Open the ORCID record for Tara N. Palmore [Opens in a new window]  and
Karen M. Frank
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Arthur H. Totten
Affiliation:
Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland
Ann Marie Matlock
Affiliation:
Nursing Department, Clinical Center, National Institutes of Health, Bethesda, Maryland
Heike Bailin
Affiliation:
Occupational Medical Service, National Institutes of Health, Bethesda, Maryland
Josanne Revoir
Affiliation:
Department of Clinical Research Informatics, Clinical Center, National Institutes of Health, Bethesda
Christopher M. Siwy
Affiliation:
Department of Clinical Research Informatics, Clinical Center, National Institutes of Health, Bethesda
Maria Joyce
Affiliation:
Department of Clinical Research Informatics, Clinical Center, National Institutes of Health, Bethesda
Patricia Coffey
Affiliation:
Health Information Management Department, Clinical Center, National Institutes of Health, Bethesda, Maryland
David K. Henderson
Affiliation:
Hospital Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland
Tara N. Palmore
Affiliation:
Hospital Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland
Karen M. Frank*
Affiliation:
Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland
Jon McKeeby
Affiliation:
Department of Clinical Research Informatics, Clinical Center, National Institutes of Health, Bethesda
*
Author for correspondence: Karen M. Frank, MD, PhD, 2C306C, Bldg 10, 10 Center Dr, Bethesda, MD 20892. E-mail: [email protected]
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Abstract

Voluntary asymptomatic severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing was provided by the NIH Clinical Center over 1 year. Among 105,927 tests, 0.2% were positive. Among eligible staff, 79% participated with variable frequency and 61% of positive individuals had symptoms at the time of testing. Saliva specimen collection was chosen as an option less frequently than midturbinate collection.

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 43 , Issue 11 , November 2022 , pp. 1661 - 1663
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Copyright
© National Institutes of Health, 2021. This is a work of the US Government and is not subject to copyright protection within the United States. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

a

Authors of equal contribution.

References

Dong, E, Du, H, Gardner, L. An interactive web-based dashboard to track COVID-19 in real time. Lancet Infect Dis 2020;20:533–534.CrossRefGoogle ScholarPubMed
He, X, Lau, EHY, Wu, P, et al. Temporal dynamics in viral shedding and transmissibility of COVID-19. Nat Med 2020;26:672–675.CrossRefGoogle ScholarPubMed
Alene, M, Yismaw, L, Assemie, MA, et al. Magnitude of asymptomatic COVID-19 cases throughout the course of infection: a systematic review and meta-analysis. PLoS One 2021;16:e0249090.CrossRefGoogle ScholarPubMed
McEllistrem, MC, Clancy, CJ, Buehrle, DJ, et al. SARS-CoV-2 is associated with high viral loads in asymptomatic and recently symptomatic healthcare workers. PLoS One 2021;16:e0248347.CrossRefGoogle ScholarPubMed
Oran, DP, Topol, EJ. The proportion of SARS-CoV-2 infections that are asymptomatic : a systematic review. Ann Intern Med 2021;174:655–662.Google ScholarPubMed
Shenoy, ES, Weber, DJ. Routine surveillance of asymptomatic healthcare personnel for severe acute respiratory coronavirus virus 2 (SARS-CoV-2): not a prevention strategy. Infect Control Hosp Epidemiol 2021. doi: 10.1017/ice.2020.1428.Google ScholarPubMed
Klompas, M, Baker, MA, Rhee, C, et al. A SARS-CoV-2 cluster in an acute-care hospital. Ann Intern Med 2021. doi: 10.7326/M20-7567.CrossRefGoogle Scholar
McKeeby, JW, Siwy, CM, Revoir, J, et al. Unveiling the silent threat among us: leveraging health information technology in the search for asymptomatic COVID-19 healthcare workers. J Am Med Inform Assoc 2021;28:377–383.CrossRefGoogle ScholarPubMed
Hanrath, AT, Schim van der Loeff, I, Lendrem, DW, et al. SARS-CoV-2 testing of 11,884 healthcare workers at an acute NHS hospital trust in England: a retrospective analysis. Front Med (Lausanne) 2021;8. doi: 10.3389/fmed.2021.636160.CrossRefGoogle ScholarPubMed
Tsang, NNY, So, HC, Ng, KY, Cowling, BJ, Leung, GM, Ip, DKM. Diagnostic performance of different sampling approaches for SARS-CoV-2 RT-PCR testing: a systematic review and meta-analysis. Lancet Infect Dis 2021. doi: 10.1016/S1473-3099(21)00146-8.CrossRefGoogle ScholarPubMed