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Does Organic Material on Hospital Surfaces Reduce the Effectiveness of Hypochlorite and UV Radiation for Disinfection of Clostridium difficile?

Published online by Cambridge University Press:  02 January 2015

Andrew Zhang ,
Michelle M. Nerandzic ,
Sirisha Kundrapu  and
Curtis J. Donskey
Andrew Zhang
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio
Michelle M. Nerandzic
Affiliation:
Research Service, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
Sirisha Kundrapu
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio
Curtis J. Donskey*
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio
*
Geriatric Research Education and Clinical Center, Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, OH 44106 ([email protected])
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Abstract

An organic load of 5%–10% fetal calf serum significantly reduced hypochlorite and UV radiation killing of Clostridium difficile spores, but organic material collected from hospital surfaces did not affect hypochlorite and only modestly affected UV killing of spores. Hypochlorite reduced aerobic microorganisms on unclean surfaces with no wiping.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 10 , October 2013 , pp. 1106 - 1108
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

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References

1.Rutala, WA, Weber, DJ; Healthcare Infection Control Practices Advisory Committee. Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008. Atlanta: Centers for Disease Control and Prevention, 2008. http://www.cdc.gov/hicpac/pdf/guidelines/disinfection_nov_2008.pdf. Accessed December 1, 2012.Google Scholar
2.Eckstein, BC, Adams, DA, Eckstein, EC, Aron, DC, Yadavalli, G, Donskey, CJ. Reduction of vancomycin-resistant Enterococcus and Clostridium difficile contamination of environmental surfaces after an intervention to improve cleaning methods. BMC Infect Dis 2007;7:61.Google Scholar
3.Nerandzic, MM, Cadnum, JL, Pultz, MJ, Donskey, JL. Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. BMC Infect Dis 2010;10:197.CrossRefGoogle ScholarPubMed
4.Sattar, SA, Springthorpe, VS, Adegbunrin, O, Zafer, AA, Busa, M. A disc-based quantitative carrier test method to assess the virucidal activity of chemical germicides. J Virol Methods 2003;112:3–12.Google Scholar
5.Boyce, JM, Havill, NL, Dumigan, DG, Golebiewski, M, Balogun, O, Rizvani, R. Monitoring the effectiveness of hospital cleaning practices by use of an adenosine triphosphate bioluminescence assay. Infect Control Hosp Epidemiol 2009;30:678–684.Google Scholar
6.Nerandzic, MM, Donskey, CJ. Effective and reduced-cost modified selective medium for isolation of Clostridium difficile. J Clin Microbiol 2009;47:397–400.Google Scholar
7.Vogel, AI. A Textbook of Quantitative Inorganic Analysis. London: Longmans, 1962:363–365.Google Scholar
8.Fertelli, D, Cadnum, JA, Nerandzic, MM, Sitzlar, B, Kundrapu, S, Donskey, CJ. Effectiveness of an electrochemically activated saline solution for disinfection of hospital equipment. Infect Control Hosp Epidemiol 2013;34:543–544.Google Scholar
9.Owens, MU, Deal, DR, Shoemaker, MO, Knudson, GB, Meszaros, JE, Deal, IL. High-dose ultraviolet C light inactivates spores of Bacillus subtilis var. niger and Bacillus anthracis Sterne on non-reflective surfaces. Appl Biosaf 2005;10:240–247.Google Scholar
10.Rutala, WA, Gergen, MF, Weber, DJ. Efficacy of different cleaning and disinfection methods against Clostridium difficile spores: importance of physical removal versus sporicidal inactivation. Infect Control Hosp Epidemiol 2012;33:1255–1258.Google Scholar