Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-25T07:16:19.896Z Has data issue: false hasContentIssue false

Current Definitions of Central Line–Associated Bloodstream Infection Is the Emperor Wearing Clothes?

Published online by Cambridge University Press:  02 January 2015

Daniel J. Sexton*
Affiliation:
Duke University Medical Center, Durham, North Carolina
Luke F. Chen
Affiliation:
Duke University Medical Center, Durham, North Carolina
Deverick J. Anderson
Affiliation:
Duke University Medical Center, Durham, North Carolina
*
Box 102359, Duke University Medical Center, Durham, North Carolina, 27710, ([email protected])

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Commentary
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Pronovost, P, Needham, D, Berenholtz, S, et al.An intervention to decrease catheter-related BSIs in the ICU. N Engl J Med 2006;355(26):27252732.Google Scholar
2.Cooper, LM, Oden, MA, Elliott, BK, Harger, IA, Anderson, DJ. Increased hand hygiene observations add validity to infection control data—but how to achieve in a busy hospital world? In: Program and abstracts of the Fifth Decennial International Conference on Healthcare-Associated Infections; Atlanta, GA; 2010.Google Scholar
3.Shuman, EK, Washer, LL, Arndt, JL, et al.Analysis of central line-associated BSIs in the intensive care unit after implementation of central line bundles. Infect Control Hosp Epidemiol 2010;31(5):551553.Google Scholar
4.National Healthcare Safety Network (NHSN). Central line-associated BSI (CLABSI) event. Updated June 2010. http://www.cdc.gov/nhsn/TOC_PSCManual.html. Accessed October 13, 2010.Google Scholar
5.O'Boyle, CJ, MacFie, J, Mitchell, CJ, Johnstone, D, Sagar, PM, Sedman, PC. Microbiology of bacterial translocation in humans. Gut 1998;42(1):2935.Google Scholar
6.MacFie, J, O'Boyle, C, Mitchell, CJ, Buckley, PM, Johnstone, D, Sudworth, P. Gut origin of sepsis: a prospective study investigating associations between bacterial translocation, gastric microflora, and septic morbidity. Gut 1999;45(2):223228.Google Scholar
7.Reddy, BS, MacFie, J, Gatt, M, Macfarlane-Smith, L, Bitzopoulou, K, Snell-ing, AM. Commensal bacteria do translocate across the intestinal barrier in surgical patients. Clin Nutr 2007;26(2):208215.Google Scholar
8.Reddy, BS, Gatt, M, Sowdi, R, MacFie, J. Surgical manipulation of the large intestine increases bacterial translocation in patients undergoing elective colorectal surgery. Colorectal Dis 2006;8(7):596600.Google Scholar
9.Woodcock, NP, Sudheer, V, El-Barghouti, N, Perry, EP, MacFie, J. Bacterial translocation in patients undergoing abdominal aortic aneurysm repair. Br I Surg 2000;87(4):439442.Google Scholar
10.Turner, JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009;9(11):799809.Google Scholar
11.Stechmiller, JK, Treloar, D, Allen, N. Gut dysfunction in critically ill patients: a review of the literature. Am J Crit Care 1997;6(3):204209.Google Scholar
12.Van Leeuwen, PA, Boermeester, MA, Houdijk, AP, et al.Clinical significance of translocation. Gut 1994;35(1 Suppl):S28S34.Google Scholar
13.Weinstein, MP, Towns, ML, Quartey, SM, et al.The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. Clin Infect Dis 1997;24(4):584602.Google Scholar
14.Weinstein, MP, Relier, LB, Murphy, IR, Lichtenstein, KA. The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations. Rev Infect Dis 1983;5(1):3553.Google Scholar
15.Beezhold, DW, Slaughter, S, Hayden, MK, et al.Skin colonization with vancomycin-resistant enterococci among hospitalized patients with bacteremia. Clin Infect Dis 1997;24(4):704706.Google Scholar
16.Hall, KK, Lyman, JA. Updated review of blood culture contamination. Clin Microbiol Rev 2006;19(4):788802.Google Scholar
17.Weinstein, MP. Blood culture contamination: persisting problems and partial progress. J Clin Microbiol 2003;41(6):22752278.Google Scholar
18.Chen, LF, Freeman, JT, Sexton, DJ, Choi, YI, Anderson, DJ. NHSN definition of laboratory-detected BSI is overly sensitive for Enterococcus. In: Program and abstracts of the 19th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America (SHEA); San Diego, CA; 2009.Google Scholar
19.Friedman, ND, Kaye, KS, Stout, IE, et al.Health care-associated BSIs in adults: a reason to change the accepted definition of community-acquired infections. Ann Intern Med 2002;137(10):791797.Google Scholar
20.McDonald, LC, Coignard, B, Dubberke, E, Song, X, Horan, T, Kutty, PK. Recommendations for surveillance of Clostridium difficile-associated disease. Infect Control Hosp Epidemiol 2007;28(2):140145.Google Scholar
21.Sassetti, CM, Rubin, EJ. The open book of infectious diseases. Nat Med 2007;13(3):279280.Google Scholar