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Colonization with Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella Species in Long-Term Care Facility Residents

Published online by Cambridge University Press:  02 January 2015

Ebbing Lautenbach ,
Jennifer Han ,
Evelyn Santana ,
Pam Tolomeo ,
Warren B. Bilker  and
Joel Maslow
Ebbing Lautenbach
Affiliation:
Division of Infectious Diseases of the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Section of Infectious Diseases, Department of Veterans Affairs, Philadelphia, Pennsylvania
Jennifer Han*
Affiliation:
Division of Infectious Diseases of the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Evelyn Santana
Affiliation:
Section of Infectious Diseases, Department of Veterans Affairs, Philadelphia, Pennsylvania
Pam Tolomeo
Affiliation:
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Warren B. Bilker
Affiliation:
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Joel Maslow
Affiliation:
Division of Infectious Diseases of the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Section of Infectious Diseases, Department of Veterans Affairs, Philadelphia, Pennsylvania
*
Division of Infectious Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 3rd Floor, Silverstein Building, Suite E, Philadelphia, PA 19104 ([email protected])
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Abstract

We describe the prevalence of and risk factors for colonization with extended-spectrum (3-lactamase-producing Enterobacteriaceae (ESBL-EB) in the long-term care facility (LTCF) setting. Colonization prevalence differed significantly across the 3 LTCFs evaluated in the study, with recent use of levofloxacin and fecal incontinence demonstrating borderline significant associations with ESBL-EB colonization.

Infect Control Hosp Epidemiol 2012;33(3):302-304

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 33 , Issue 3 , March 2012 , pp. 302 - 304
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2012

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References

1. Schwaber, MJ, Navon-Venezia, S, Kaye, KS, Ben-Ami, R, Schwartz, D, Carmeli, Y. Clinical and economic impact of bacteremia with extended-spectrum-β-lactamase-producing Enterobacteriaceae. Antimicrob Agents Chemother 2006;50:1257–1262.Google Scholar
2. Pena, C, Pujol, M, Ricart, A, et al. Risk factors for faecal carriage of Klebsiella pneumoniae producing extended spectrum β-lactamase (ESBL-KP) in the intensive care unit. J Hosp Infect 1997;35:9–16.Google Scholar
3. Du, B, Long, Y, Liu, H, et al. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae bloodstream infection: risk factors and clinical outcome. Intensive Care Med 2002;28:1718–1723.Google Scholar
4. O'Fallon, E, Kandel, R, Schreiber, R, D'Agata, EM. Acquisition of multidrug-resistant gram-negative bacteria: incidence and risk factors within a long-term care population. Infect Control Hosp Epidemiol 2010;31:1148–1153.CrossRefGoogle ScholarPubMed
5. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing. Wayne, PA: CLSI, 2010. CLSI document M100-S20.Google Scholar
6. Tenover, FC, Arbeit, RD, Goering, RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233–2239.Google Scholar
7. Mendelson, G, Hait, V, Ben-Israel, J, Gronich, D, Granot, E, Raz, R. Prevalence and risk factors of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in an Israeli long-term care facility. Eur J Clin Microbiol Infect Dis 2005;24:17–22.CrossRefGoogle Scholar
8. Yoo, JS, Byeon, J, Yang, J, Yoo, JI, Chung, GT, Lee, YS. High prevalence of extended-spectrum β-lactamases and plasmid-mediated AmpC β-lactamases in Enterobacteriaceae isolated from long-term care facilities in Korea. Diagn Microbiol Infect Dis 2010;67:261–265.CrossRefGoogle ScholarPubMed
9. March, A, Aschbacher, R, Dhanji, H, et al. Colonization of residents and staff of a long-term-care facility and adjacent acute-care hospital geriatric unit by multiresistant bacteria. Clin Microbiol Infect 2010;16:934–944.Google Scholar
10. Rooney, PJ, O'Leary, MC, Loughrey, AC, et al. Nursing homes as a reservoir of extended-spectrum β-lactamase (ESBL)-producing ciprofloxacin-resistant Escherichia coli . J Antimicrob Chemother 2009;64:635–641.Google Scholar