Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-23T07:18:41.310Z Has data issue: false hasContentIssue false
  • English
  • Français

Clostridium difficile Infections in Outpatient Dialysis Cohort

Published online by Cambridge University Press:  02 January 2015

Heena Sheth ,
Judith Bernardini ,
Renee Burr ,
Sophie Lee ,
Rachel G. Miller ,
Michele Shields ,
Emanuel N. Vergis  and
Beth Piraino
Heena Sheth*
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
Judith Bernardini
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
Renee Burr
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
Sophie Lee
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
Rachel G. Miller
Affiliation:
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania
Michele Shields
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
Emanuel N. Vergis
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
Beth Piraino
Affiliation:
Department of Medicine, University of Pittsburgh Medical Center and School of Medicine, Pittsburgh, Pennsylvania
*
Department of Medicine, 3504 Fifth Avenue, Suite 200, Pittsburgh, PA 15213 ([email protected])
Get access Rights & Permissions [Opens in a new window]

Extract

We examined the Clostridium difficile infection rate and risk factors in an outpatient dialysis cohort. The Cox proportional hazard for developing C. difficile infection was significantly higher with high comorbidity index and low serum albumin level. Conversely, it was lower for patients who had frequent bloodstream and dialysis access-related infections.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 31 , Issue 1 , January 2010 , pp. 89 - 91
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Centers for Disease Control and Prevention. Clostridium difficile information for healthcare providers. Released August 2004. Updated July 22, 2005. Available at: http://www.cdc.gov/ncidod/dhqp/id_Cdiff.html. Accessed June 10, 2009.Google Scholar
2.Larson, H, Price, A, Honour, P, Borriello, S. Clostridium difficile and the etiology of pseudomembranous colitis. Lancet 1978;1:1063–1066.Google Scholar
3.Thibault, A, Miller, M, Gaese, C. Risk factors for the development of Clostridium difficile-associated diarrhea during a hospital outbreak. Infect Control Hosp Epidemiol 1991;12:345–348.CrossRefGoogle ScholarPubMed
4.Bignardi, G. Risk factors for Clostridium difficile infection. J Hosp Infect 1998;40:1–15.CrossRefGoogle ScholarPubMed
5.Cunney, R, Magee, C, McNamara, E, Smyth, E, Walsh, J. Clostridium difficile colitis associated with chronic renal failure. Nephrol Dial Transplant 1998;13:2842–2846.CrossRefGoogle ScholarPubMed
6.Charlson, M, Pompei, P, Ales, K, MacKenzie, C. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373–383.CrossRefGoogle ScholarPubMed
7.Dubberke, ER, Reske, KA, Yan, Y, Olsen, MA, ML, C, Fraser, V. Clostridium difficile–associated disease in a setting of endemicity: identification of novel risk factors. Clin Infect Dis 2007;45:1543–1549.CrossRefGoogle Scholar
8.Leung, A, Orange, G, McLay, A, Henderson, I. Clostridium difficile-associated colitis in uremic patients. Clin Nephrol 1985;24:242–248.Google ScholarPubMed
9.Gorbach, S. Antibiotics and Clostridium difficile. N Engl J Med 1999;341:1690–1691.CrossRefGoogle ScholarPubMed
10.Barany, P, Stevinkel, P, Nord, C, Bergstrom, J. Clostridium difficile infection-a poor prognostic sign in uremic patients? Clin Nephrol 1992;38:53–57.Google ScholarPubMed