Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T21:43:40.246Z Has data issue: false hasContentIssue false
  • English
  • Français

An Investigation of the Bactericidal Effect of Certain Antiseptics and Disinfectants on Some Hospital Isolates of Gram-Negative Bacteria

Published online by Cambridge University Press:  02 January 2015

Melike Tunçay Ekizoglu ,
Meral Özalp ,
Nedim Sultan  and
Deniz Gür
Melike Tunçay Ekizoglu
Affiliation:
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey
Meral Özalp*
Affiliation:
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey
Nedim Sultan
Affiliation:
Department of Medical Microbiology, Faculty of Medicine, Gazi University, Ankara, Turkey
Deniz Gür
Affiliation:
Ihsan Dogramaci Children's Hospital, Clinical Microbiology Laboratory, Hacettepe University, Ankara, Turkey
*
Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, 06100 Ankara, Turkey
Get access Rights & Permissions [Opens in a new window]

Abstract

The effect of widely used antiseptics and disinfectants on some hospital isolates of gram-negative bacteria was assessed by the quantitative suspension test. Chlorhexidine gluconate (4%), savlon (1:100), and 5.25% sodium hypochlorite were tested. Savlon and chlorhexidine gluconate were effective at in-use concentrations and sodium hypochlorite was effective at 1:50 dilution.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 24 , Issue 3 , March 2003 , pp. 225 - 227
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Griffiths, PA, Babb, JR, Bradley, CR, Fraise, ARGlutaraldehyde-resistant Mycobacterium chelonae from endoscope washer disinfectors. J Appl Microbiol 1997;82:519–526.CrossRefGoogle ScholarPubMed
2.Russell, AD, Day, MJ. Antibacterial activity of Chlorhexidine. J Hosp Infect 1993;25:229–238.CrossRefGoogle ScholarPubMed
3.Wolf, AA. Anhydrous sodium thiosulfate as a primary iodometric standard. Anal Chem 1982;54:2134–2136.CrossRefGoogle Scholar
4.Rutala, W, Weber, DJ. Uses of inorganic hypochlorite (bleach) in healthcare facilities. Clin Microbiol Rev 1997;10:597–610.CrossRefGoogle Scholar
5.Coates, D, Hutchinson, DN. How to produce a hospital disinfection policy. J Hosp Infect 1994;26:57–68.CrossRefGoogle ScholarPubMed
6.Reybrouck, G. A comparison of the quantitative suspension tests for the assessment of disinfectants. Zbl Bad Hygl Abt Orig B 1980;170:449–456.Google ScholarPubMed
7.Bloomfield, SF, Arthur, M, Looney, E, Begun, K, Patel, H. Comparative testing of disinfectant and antiseptic products using proposed European suspension testing methods. Lett Appl Microbiol 1991;13:233–237.CrossRefGoogle Scholar
8.Hammond, SA, Morgan, JR, Russell, AD. Comparative susceptibility of hospital isolates of gram-negative bacteria to antiseptics and disinfectants. J Hosp Infect 1987;9:255–264.CrossRefGoogle ScholarPubMed
9.Payne, DN, Babb, JR, Bradley, CR. An evaluation of the European suspension test to reflect in vitro activity of antiseptics against clinically significant organisms. Lett Appl Microbiol 1999;28:7–12.CrossRefGoogle ScholarPubMed
10.Sagripanti, JL, Eklund, CA, Trost, PA, et al.Comparative sensitivity of 13 species of pathogenic bacteria to seven chemical germicides. Am J Infect Control 1997;25:335–339.CrossRefGoogle ScholarPubMed
11.Rutala, WA, Cole, CC, Thomann, CA, Weber, DJ. Stability and bactericidal activity of chlorine solutions. Infect Control Hosp Epidemiol 1998;19:323–327.CrossRefGoogle ScholarPubMed