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Airborne Severe Acute Respiratory Syndrome Coronavirus Concentrations in a Negative-Pressure Isolation Room

Published online by Cambridge University Press:  21 June 2016

Ying-Huang Tsai ,
Gwo-Hwa Wan ,
Yao-Kuang Wu  and
Kuo-Chien Tsao
Ying-Huang Tsai
Affiliation:
Departments of Pulmonary and Critical Care, Chang Gung Memorial Hospital, Taiwan, Republic of China
Gwo-Hwa Wan*
Affiliation:
Department of Respiratory Care, College of Medicine, Chang Gung University, Taiwan, Republic of China
Yao-Kuang Wu
Affiliation:
Departments of Pulmonary and Critical Care, Chang Gung Memorial Hospital, Taiwan, Republic of China
Kuo-Chien Tsao
Affiliation:
Clinical Pathology, Chang Gung Memorial Hospital, Taiwan, Republic of China
*
Department of Respiratory Care, College of Medicine, Chang Gung University, 259, Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, Taiwan, Republic of China ([email protected])
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Abstract

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This study used a sensitive polymerase chain reaction method coupled with filter sampling to detect the presence of airborne severe acute respiratory syndrome (SARS) coronavirus in an isolation patient room with a patient with severe acute respiratory syndrome receiving mechanical ventilatory support. Polymerase chain reaction results were negative for SARS coronavirus in room air both before and after patient extubation.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 27 , Issue 5 , May 2006 , pp. 523 - 525
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

References

1.Drosten, C, Gunther, S, Preiser, W, et al. Identification of a novel Coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003; 348:1967–1976.Google Scholar
2.World Health Organization (WHO). Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003. Available at: http://www.who.int/csr/sars/country/table2004_04_21/en/.Google Scholar
3.Inouye, S. SARS transmission: language and droplet production. Lancet 2003; 362:170.Google Scholar
4.Duguid, JP. The size and duration of air carriage of respiratory droplets and droplet nuclei. J Hyg 1946; 44:471–479.Google Scholar
5.Ksiazek, TG, Erdman, D, Goldsmith, CS, et al. A novel Coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003; 348:1953–1966.Google Scholar
6.World Health Organization (WHO). First data on stability and resistance of SARS Coronavirus complied by members of WHO laboratory network. Available at: http://www.who.int/csr/sars/survival_2003_05_04/en/index.html.Google Scholar
7.Koubek, C, Loose, C, Sottili, C. Protecting yourself as SARS fears increase. Washington Post April 13, 2003.Google Scholar
8.Lau, JTF, Yang, X, Leung, PC, et al. SARS in three categories of hospital workers, Hong Kong. Emerg Infect Dis 2004; 10:1399–1404.Google Scholar
9.Teleman, MD, Boudville, IC, Heng, BH, Zhu, D, Leo, YS. Factors associated with transmission of severe acute respiratory syndrome among healthcare workers in Singapore. Epidemiol Infect 2004; 132:797–803.Google Scholar
10.Li, Y, Huang, X, Yu, ITS, Wong, TW, Qian, H. Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong. Indoor Air 2004; 15:83–95.Google Scholar
11.Sawyer, MH, Chamberlin, CJ, Wu, YN, Aintablian, N, Wallace, MR. Detection of varicella-zoster DNA in air samples from hospital rooms. J Infect Dis 1994; 169:91–94.Google Scholar
12.McCluskey, R, Sandin, R, Greene, J. Detection of airborne Cytomegalovirus in hospital rooms of immunocompromised patients. J Virol Methods 1996; 56:115–118.Google Scholar
13.Myatt, TA, Johnston, SL, Rudnick, S, Milton, DK. Airborne rhinovirus detection and effect of ultraviolet irradiation on detection by a semi-nested RT-PCR assay. BioMed Central Public Health 2003; 3:5.CrossRefGoogle ScholarPubMed
14.Wan, GH, Tsai, YH, Wu, YK, Tsao, KC. A large-volume nebulizer would not be an infectious source for severe acute respiratory syndrome (SARS). Infect Control Hosp Epidemiol 2004; 25:1113–1115.Google Scholar
15.Taiwan's Center for Disease Control and Prevention. Standard Operation Procedures for Real-time RT-PCR in SARS-Related Coronavirus Identification. Taipei, Taiwan: Taiwan's Center for Disease Control and Prevention; 2003. Document No. CDC-LAB-MSOP-073.Google Scholar