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Time to positivity of blood cultures among a veteran population: How long to wait before discontinuing antimicrobial therapy when suspicion of infection is low

Published online by Cambridge University Press:  21 July 2020

Brett H. Heintz ,
Zach T. DeLanoit ,
Leah J. Granroth  and
Whitni T. Patterson
Brett H. Heintz
Affiliation:
University of Iowa College of Pharmacy, Iowa City, Iowa Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa Iowa City VA Health Care System, Iowa City, IA
Zach T. DeLanoit*
Affiliation:
M Health Fairview, University of Minnesota Medical Center, Minneapolis, Minnesota
Leah J. Granroth
Affiliation:
Phoenix VA Health Care System, Phoenix, Arizona
Whitni T. Patterson
Affiliation:
University of Iowa Hospitals and Clinics, Iowa City, Iowa
*
Author for correspondence: Zach Delanoit, E-mail: [email protected]
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Abstract

Time to positivity (TTP) of blood cultures can guide antimicrobial therapy. This single-center retrospective cohort study aimed to determine the yield of clinically significant organisms from blood cultures that were initially negative at 24 hours. Clinically significant organisms were uncommon after 24 hours (1.5%) and more common in intensive care unit settings.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 41 , Issue 12 , December 2020 , pp. 1452 - 1454
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Copyright
© 2020 by The Society for Healthcare Epidemiology of America. All rights reserved.

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