Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-19T08:27:36.718Z Has data issue: false hasContentIssue false

Nosocomial Pertussis Outbreak Among Adult Patients and Healthcare Workers

Published online by Cambridge University Press:  02 January 2015

Laurence Bassinet
Affiliation:
Service de Pneumotogie et de Pathologic Professionnelle, Centre Hospitaller Intercommunal de Créteil, Créteil, France Institut Pasteur, Unité Prévention et Thérapie Moléculaires des Maladies Humaines, Centre National de Référence de la Coqueluche et Autres Bordetelloses, Paris, France
Mireille Matrat
Affiliation:
Service de Pneumotogie et de Pathologic Professionnelle, Centre Hospitaller Intercommunal de Créteil, Créteil, France
Elisabeth Njamkepo
Affiliation:
Institut Pasteur, Unité Prévention et Thérapie Moléculaires des Maladies Humaines, Centre National de Référence de la Coqueluche et Autres Bordetelloses, Paris, France
Said Aberrane
Affiliation:
Service de Bactériologie, Centre Hospitalier Intercommunal de Cretéil, Cretéil, France
Bruno Housset
Affiliation:
Service de Pneumotogie et de Pathologic Professionnelle, Centre Hospitaller Intercommunal de Créteil, Créteil, France
Nicole Guiso*
Affiliation:
Institut Pasteur, Unité Prévention et Thérapie Moléculaires des Maladies Humaines, Centre National de Référence de la Coqueluche et Autres Bordetelloses, Paris, France
*
Institut Pasteur, Unité Prévention et Thérapie Moléculaires des Maladies Humaines, 25 rue du Dr Roux, 75724 Paris Cedex 15, France

Abstract

We describe a pertussis outbreak among adult patients in a French general hospital following transmission from a healthcare worker. This index case transmitted pertussis to other healthcare workers, who, in turn, contaminated other staff and two immuno-suppressed patients. This raises questions about infection control.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2004

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Wirsing von Konig, CH, Halperin, S, Riffelmann, M, Guiso, N. Pertussis of adults and infants. Lancet Infect Dis 2002;2:744750.Google Scholar
2. Christie, CD, Glover, AM, Willke, MJ, Marx, ML, Reising, SF, Hutchinson, NM. Containment of pertussis in the regional pediatric hospital during the Greater Cincinnati epidemic of 1993. Infect Control Hosp Epidemiol 1995;16:556563.CrossRefGoogle ScholarPubMed
3. Gilberg, S, Njamkepo, E, Parent du Chatelet, I, et al. Evidence of Bordetella pertussis infection in adults presenting with persistent cough in a French area with very high whole-cell vaccine coverage. J Infect Dis 2002;186:415418.Google Scholar
4. De Melker, HE, Versteegh, FGA, Conyn-van Spaendonck, MAE, et al. Specificity and sensitivity of high levels of immunoglobulin G antibodies against pertussis toxin in a single serum sample for diagnosis of infection with Bordetella pertussis . J Clin Microbiol 2000;38:800806.Google Scholar
5. Swinker, M. Occupational infections in health care workers: prevention and intervention. Am Earn Physician 1997;56:22912300.Google ScholarPubMed
6. Nouvellon, M, Gehanno, JF, Pestel-Caron, M, Weber, C, Lemeland, JF, Guiso, N. Usefulness of pulsed-field gel-electrophoresis in assessing nosocomial pertussis transmission. Infect Control Hosp Epidemiol 1999;20:758760.CrossRefGoogle Scholar
7. Fisher, MC, Long, SS, McGowan, KL, Kaselis, E, Smith, DG. Outbreak of pertussis in a residential facility for handicapped people. J Pediatr 1989;114:934939.Google Scholar
8. Tanaka, Y, Fujinaga, K, Goto, A et al. Outbreak of pertussis in a residential facility for handicapped people. Developments of Biological Standardization 1991;73:329332.Google Scholar
9. Cohn, SE, Knorr, KL, Gilligan, PH, Smiley, ML, Weber, DJ. Pertussis is rare in human immunodeficiency virus disease. American Review of Respiratory Disease 1993;147:411413.Google Scholar
10. MacLean, DW. Bordetella pertussis infection in patients with bronchogenic carcinoma. Lancet 1981;1:503504. Letter.Google Scholar
11. Ward, A, Caro, J, Bassinet, L, Housset, B, O'Brien, J, Guiso, N. Economic-consequences of an outbreak of pertussis amongst healthcare workers in a hospital in France. Presented at the 43rd Annual Interscience Conference on Antimicrobial Agents and Chemotherapy; September 1417, 2003; Chicago, IL.Google Scholar