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Nasal and Cutaneous Carriage of Staphylococcus aureus in Hemodialysis Patients: The Effect of Nasal Mupirocin

Published online by Cambridge University Press:  02 January 2015

Abstract

Fifteen of 20 hemodialysis patients who carried Staphylococcus aureus in their nares also carried the organism on their hands; 2 of 20 patients who did not carry S aureus in their nares carried S aureus on their hands (P<.001). Eightyseven percent of patients who carried S aureus in their nares and on their hands carried the same strain at both sites. Intranasal mupirocin eliminated S aureus from both sites.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1996

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References

1. Boelaert, JR, Daneels, RF, Schurgers, ML, Matthys, EG, Gordts, BZ, Van Landuyt, HW. Iron overload in haemodialysis patients increases the risk of bacteraemia: a prospective study. Nephrol Dial Transplant 1990;5:130134.CrossRefGoogle ScholarPubMed
2. Chow, JW, Yu, VL. Staphylococcus aureus nasal carriage in hemodialysis patients. Its role in infection and approaches to prophylaxis. Arch Intern Med 1989;149:12581262.CrossRefGoogle ScholarPubMed
3. Boelaert, JR, De Smedt, R, De Baere, YA, et al. The influence of calcium mupirocin nasal ointment on the incidence of Staphylococcus aureus infections in haemodialysis patients. Nephrol Dial Transplant 1989;4:278281.CrossRefGoogle ScholarPubMed
4. Kirmani, N, Tuazon, CU, Murray, HW, et al. Staphylococcus aureus carriage rate of patients receiving long-term hemodialysis. Arch Intern Med 1978;138:16571659.CrossRefGoogle ScholarPubMed
5. Holton, DL, Nicolle, LE, Diley, D, et al. Efficacy of mupirocin nasal ointment in eradicating Staphylococcus aureus nasal carriage in chronic haemodialysis patients. J Hosp Infect 1991;17:133137.CrossRefGoogle ScholarPubMed
6. Ena, J, Boelaert, JR, Boyken, L, Van Landuyt, HW, Godard, CA, Herwaldt, LA. Epidemiology of infections in nasal carriers of S aureus on haemodialysis. Infect Control Hosp Epidemiol 1994;15:7881.CrossRefGoogle Scholar
7. Boelaert, JR, Van Landuyt, JW, Godard, CA, et al. Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemia in haemodialysis patients. Nephrol Dial Transplant 1993;8:235239.Google ScholarPubMed
8. Reagan, DR, Doebbeling, BN, Pfaller, MA, et al. Elimination of coincident Staphylococcus aureus nasal and hand carriage with intranasal application of mupirocin calcium ointment. Ann Intern Med 1991;114:101106.CrossRefGoogle ScholarPubMed
9. Pfaller, M, Hollis, RJ, Sader, HS. Pulsed field gel electrophoresis of chromosomal DNA. In: Isenberg, HD, ed. Clinical Microbiology Procedures Handbook. Washington, DC: American Society for Microbiology; 1992:10.5.c.Google Scholar