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Multicenter, Prospective Surveillance Study of Staphylococcus aureus Nasal Colonization in 28 Italian Intensive Care Units: The ISABEL Study

Published online by Cambridge University Press:  02 January 2015

Pierluigi Viale ,
Giovanni Gesu ,
Gaetano Privitera ,
Biagio Allaria ,
Nicola Petrosillo ,
Eleonora Zamparini ,
Luigia Scudeller  and
ISABEL Study Group
Pierluigi Viale*
Affiliation:
Clinica di Malattie Infettive, University of Bologna, Bologna, Italy
Giovanni Gesu
Affiliation:
Department of Microbiology, Ospedale Niguarda, Milan, Italy
Gaetano Privitera
Affiliation:
Experimental Disease Department, University of Pisa, Pisa, Italy
Biagio Allaria
Affiliation:
Resuscitation Service, Istituto dei Tumori, Milan, Italy
Nicola Petrosillo
Affiliation:
Second Infectious Diseases Division, National Institute for Infectious Diseases “L. Spallanzani,”Rome, Italy
Eleonora Zamparini
Affiliation:
Clinica di Malattie Infettive, University of Udine, Udine, Italy
Luigia Scudeller
Affiliation:
Clinical Epidemiology Unit, IRCCS Policlinico San Matteo, Pavia, Italy
*
Clinica di Malattie Infettive, University of Bologna, Policlinico S. Orsola-Malpighi, via Massarenti 11, 40138 Bologna, Italy ([email protected])
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Extract

The role of methicillin-resistant Staphylococcus aureus (MRSA) colonization as a predictor of invasive disease in intensive care unit (ICU) patients was established many years ago. The role of mefhicillin-susceptible Staphylococcus aureus (MSSA) colonization is more debated, although in a recent report patients who were carriers of MRSA or MSSA at ICU admission were found to be at increased risk. Whether carriage at ICU admission involves a higher risk of invasive infection than carriage acquired during an ICU stay has not been established. We report the results of a study aimed at estimating the frequency of S. aureus (MRSA and MSSA) colonization at admission and at discharge in patients admitted to several ICUs in Italy and at estimating the relationship between colonization status and infection by S. aureus.

Type
Research Briefs
Information
Infection Control & Hospital Epidemiology , Volume 32 , Issue 2 , February 2011 , pp. 193 - 197
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2011

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