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Management of carbapenemase-producing Enterobacteriaceae in a low incidence area: A six-year experience in a university hospital

Published online by Cambridge University Press:  17 June 2019

Audrey Emery ,
Audrey Jeanvoine ,
Pascale Bailly ,
Houssein Gbaguidi-Haore ,
Didier Hocquet  and
Xavier Bertrand
Audrey Emery
Affiliation:
Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, Besançon, France
Audrey Jeanvoine
Affiliation:
Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, Besançon, France UMR 6249 Chrono-environnement, Université de Bourgogne-Franche-Comté, Besançon, France
Pascale Bailly
Affiliation:
Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, Besançon, France
Houssein Gbaguidi-Haore
Affiliation:
Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, Besançon, France UMR 6249 Chrono-environnement, Université de Bourgogne-Franche-Comté, Besançon, France
Didier Hocquet
Affiliation:
Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, Besançon, France UMR 6249 Chrono-environnement, Université de Bourgogne-Franche-Comté, Besançon, France Centre de Ressources Biologiques – Filière Microbiologique de Besançon, Centre Hospitalier Régional Universitaire, Besançon, France
Xavier Bertrand*
Affiliation:
Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, Besançon, France UMR 6249 Chrono-environnement, Université de Bourgogne-Franche-Comté, Besançon, France
*
Author for correspondence: Xavier Bertrand, Hygiène Hospitalière, Centre Hospitalier Régional Universitaire, 3 boulevard Fleming, Besançon, Cedex 25030, France. Email: [email protected]
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Abstract

We conducted a 6-year retrospective analysis of monitoring of carbapenemase-producing Enterobacteriaceae (CPE) in a large hospital in a low CPE incidence area, and we evaluated the “search and isolate” strategy implemented. In total, 40 CPE isolates were collected from 32 patients, and only 1.4% of contact patients screened were CPE carriers.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 40 , Issue 8 , August 2019 , pp. 936 - 938
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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References

Cantón, R, Akóva, M, Carmeli, Y, et al. Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe. Clin Microbiol Infect 2012;18:413–431.CrossRefGoogle Scholar
HCSP. Prévention de la transmission croisée des Bactéries Hautement Résistantes aux antibiotiques émergentes (BHRe). Paris: Haut Conseil de la Santé Publique; 2013.Google Scholar
Clinical breakpoints and dosing of antibiotics EUCAST website. http://www.eucast.org/clinical_break. Published 2019. Accessed January 16, 2019.Google Scholar
Hrabák, J, Chudáčkova, E, Papagiannitsis, CC. Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories. Clin Microbiol Infect 2014;20:839–853.CrossRefGoogle ScholarPubMed
Tenover, FC, Arbeit, RD, Goering, RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:2233–2239.Google ScholarPubMed
Birgand, G, Leroy, C, Nerome, S, et al. Costs associated with implementation of a strict policy for controlling spread of highly resistant microorganisms in France. BMJ Open 2016;6:e009029.CrossRefGoogle ScholarPubMed
Poirel, L, Potron, A, Nordmann, P. OXA-48-like carbapenemases: the phantom menace. J Antimicrob Chemother 2012;67:1597–1606.CrossRefGoogle ScholarPubMed
Potron, A, Poirel, L, Nordmann, P. Derepressed transfer properties leading to the efficient spread of the plasmid encoding carbapenemase OXA-48. Antimicrob Agents Chemother 2014;58:467–471.CrossRefGoogle ScholarPubMed
De Geyter, D, Blommaert, L, Verbraeken, N, et al. The sink as a potential source of transmission of carbapenemase-producing Enterobacteriaceae in the intensive care unit. Antimicrob Resist Infect Control 2017;6:24.CrossRefGoogle ScholarPubMed