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Implementation and Evaluation of an Algorithm for Isolation of Patients With Suspected Pulmonary Tuberculosis

Published online by Cambridge University Press:  02 January 2015

Clare F. Pegues
Affiliation:
Infection Control Unit, Massachusetts General Hospital, Boston, Massachusetts Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, Massachusetts Infectious Disease Unit, Massachusetts General Hospital, Boston, Massachusetts
David A. Pegues
Affiliation:
Infection Control Unit, Massachusetts General Hospital, Boston, Massachusetts Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston, Massachusetts
Maureen Spencer
Affiliation:
Infection Control Unit, Massachusetts General Hospital, Boston, Massachusetts
Cyrus C. Hopkins
Affiliation:
Infection Control Unit, Massachusetts General Hospital, Boston, Massachusetts Infectious Disease Unit, Massachusetts General Hospital, Boston, Massachusetts

Abstract

Objective: To implement and evaluate an algorithm designed to assist in the consistent placement of patients with suspected pulmonary tuberculosis into negative-pressure isolation rooms (NPIRs).

Design: A standard algorithm was designed for the appropriate room placement of patients with suspected pulmonary tuberculosis using clinical, radiographic, and laboratory criteria and reported risk factors. A case-patient was defined as an inpatient who had at least one Mycobacterium tuberculosis culture-positive respiratory specimen from January 1, 1993, through December 31, 1994. Demographic, clinical, laboratory, case contact, and isolation and room placement data were collected prospectively on all case-patients.

Setting: A 900-bed university teaching and referral center.

Results: During 1993 and 1994, 69 patients were evaluated for possible pulmonary tuberculosis, and 31 case-patients were identified. Of the 31 case-patients, 26 (84%) were placed on respiratory isolation in NPIRs, including 19 (61%) who were isolated within 24 hours of admission (1993, 14 of 20 [70%]; 1994, 5 of 11 [45%]). Seven case-patients (23%) were isolated in NPIRs following delays that ranged from 2 to 31 days (median, 9 days), and five case-patients (16%) never were isolated during admissions of from 3 to 28 days (median, 4 days). These 12 case-patients contributed a total of 136 patient-exposure days during their hospitalizations. Misclassification of patient risk status by user error delayed isolation of five (42%) of the 12 improperly isolated case-patients.

Conclusions: The use of an algorithm incorporating radiographic, laboratory, and clinical criteria and reported risk factors may assist in the rapid isolation of patients with suspected pulmonary tuberculosis.

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1996

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References

1. Ellner, JJ, Hinman, AR, Dooley, SW, et al. Tuberculosis symposium: emerging problems and promise. JAMA 1993;168:537551.Google ScholarPubMed
2. Barnes, PF, Barrows, SA. Tuberculosis in the 1990’s. Ann Intern Med 1993;119:400410.Google Scholar
3. Gordin, F. Tuberculosis control: back to the future? JAAMA 1992;267:26492650.CrossRefGoogle ScholarPubMed
4. Snider, DE Jr, Roper, WL. The new tuberculosis. N Engl J Med 1992;326:703705.Google Scholar
5. Hopewell, PC. Impact of human immunodeficiency virus on the epidemiology, clinical features, management, and control of tuberculosis. Clin Infect Dis 1992;15:540547.Google Scholar
6. Brudney, K, Dobkin, J. Resurgent tuberculosis in New York City: human immunodeficiency virus, homelessness and the decline of tuberculosis control programs. Am Rev Respir Dis 1991;144:745749.CrossRefGoogle ScholarPubMed
7. OSHA enforcement policy: procedures for occupational exposure to tuberculosis. Infect Control Hosp Epidemiol 1993;14:694699.Google Scholar
8. Centers for Disease Control and Prevention. Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-car–facilities, 1994. MMWR 1994;43(RR-13):1132.Google Scholar
9. Centers for Disease Control. Guidelines for preventing the transmission of tuberculosis in health-care settings, with special focus on HIV-related issues. MMWR 1990;39(RR-17):129.Google Scholar
10. Garner, JS, Simmons, BP. Guidelines for isolation precautions in hospitals. Infect Control 1983;4:245325.Google Scholar
11. Centers for Disease Control and Prevention. Core Curriculum on Tuberculosis: What the Clinician Should Know. 3rd ed. Atlanta, GA: US Public Health Service; 1994:7, 5354.Google Scholar
12. Centers for Disease Control. Nosocomial transmission of multidrug-resistant tuberculosis among HIV-infected persons—Florida and New York, 1988-1991. MMWR 1991;40:585591.Google Scholar
13. Pearson, ML, Jereb, JL, Frieden, TR, et al. Nosocomial transmission of Mycobacterium tuberculosis:a risk to patients and healthcare workers. Ann Intern Med 1992;117:191196.CrossRefGoogle Scholar
14. McGowan, JE. Resurgent nosocomial tuberculosis: consequences and actions for hospital epidemiologists. Infect Control Hosp Epidemiol 1992;13:575578.Google Scholar
15. Nicas, M, Sprinson, JE, Royce, SE, et al. Isolation rooms for tuberculosis control. Infect Control Hosp Epidemiol 1993;14:619622. Editorial.CrossRefGoogle ScholarPubMed
16. Neill, HM. Isolation-room ventilation critical to control disease. Health Facilities Management 1992;9:3038.Google Scholar
17. American Thoracic Society, Centers for Disease Control. Diagnostic standards and classification of tuberculosis. Am Rev Respir Dis 1990;142:725735.Google Scholar
18. Pitchenik, AE, Rubinson, HA. The radiographic appearance of tuberculosis in patients with the acquired immune deficiency syndrome (AIDS) and pre-AIDS. Am Rev Respir Dis 1985;131:393396.Google Scholar
19. Chaisson, RE, Schecter, GF, Theuer, CP, et al. Tuberculosis in patients with the acquired immunodeficiency syndrome. Am Rev Respir Dis 1987;136:570574.Google Scholar
20. Klein, NC, Duncanson, FP, Lenox, TH III, et al. Use of mycobacterial smears in the diagnosis of pulmonary tuberculosis in AIDS/ARC patients. Chest 1989;95:11901192.CrossRefGoogle ScholarPubMed