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The effect of body mass index on the risk of surgical site infection

Published online by Cambridge University Press:  24 June 2019

Anouk P. Meijs ,
Mayke B.G. Koek ,
Margreet C. Vos ,
Suzanne E. Geerlings ,
H. Charles Vogely  and
Sabine C. de Greeff
Anouk P. Meijs*
Affiliation:
Department of Epidemiology and Surveillance, Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
Mayke B.G. Koek
Affiliation:
Department of Epidemiology and Surveillance, Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
Margreet C. Vos
Affiliation:
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands
Suzanne E. Geerlings
Affiliation:
Department of Internal Medicine, Division of Infectious Diseases, Amsterdam University Medical Center, The Netherlands
H. Charles Vogely
Affiliation:
Department of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands
Sabine C. de Greeff
Affiliation:
Department of Epidemiology and Surveillance, Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands
*
Author for correspondence: Anouk P. Meijs, Email: [email protected]
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Abstract

Objective:

Obesity is considered a risk factor for surgical site infection (SSI). We quantified impact of body mass index (BMI) on the risk of SSI for a variety of surgical procedures.

Methods:

We included 2012–2017 data from the Dutch national surveillance network PREZIES on a selection of frequently performed surgical procedures across different specialties. Patients were stratified into 5 categories: underweight (BMI, <18.5 kg/m2), normal weight (BMI, 18.5–25), overweight (BMI, 25–30), obese (BMI, 30–40) and morbidly obese (BMI, ≥40). Multilevel log binomial regression analyses were performed to assess the effect of BMI category on the risk of superficial, deep (including organ-space) and total SSI.

Results:

Of the 387,919 included patients (ranging from 2,616 for laparoscopic appendectomy to 119,834 for total hip prosthesis), 3,676 (1%) were underweight, 116,778 (30%) had normal weight, 154,339 (40%) were overweight, 104,288 (27%) had obesity, and 8,838 (2%) were morbidly obese. A trend of increasing risk of SSI when BMI increased from normal to morbidly obese was observed for almost all surgery types. The increase was most profound in surgeries with clean wounds, with relative risks for morbidly obese patients ranging up to 7.8 (95% CI, 6.0–10.2) for deep SSI in total hip prosthesis. In chest and abdominal surgeries, the impact was larger for superficial SSI than for deep SSI.

Conclusions:

The results of our research provide evidence for the need of preventive programs targeting SSI in overweight and obese patients, as well as for the prevention of obesity in the general population.

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 40 , Issue 9 , September 2019 , pp. 991 - 996
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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