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Correlation Between Respiratory Colonization With Gram-Negative Bacteria and Development of Gram-Negative Bacterial Infection After Cardiac Surgery

Published online by Cambridge University Press:  02 January 2015

Pranavi V. Sreeramoju*
Affiliation:
Department of Medicine-Infectious Diseases, University of Chicago
Sylvia Garcia-Houchins
Affiliation:
Department of Infection Control, University of Chicago Medical Center
Judith Bova
Affiliation:
Department of Infection Control, University of Chicago Medical Center
Cynthia C. Kelly
Affiliation:
Department of Medicine-Infectious Diseases, University of Texas Health Sciences Center, San Antonio, Texas
Stephen G. Weber
Affiliation:
Department of Medicine-Infectious Diseases, University of Chicago Department of Infection Control, University of Chicago Medical Center
*
7703 Floyd Curl Drive, MC 7881, San Antonio, TX 78229 ([email protected])

Abstract

This pilot, observational study involving 286 patients who underwent cardiac surgery found that patients who had endotracheal colonization with gram-negative bacteria at 1 week after surgery were more likely to develop subsequent infection compared to those without colonization (8 of 23 vs. 4 of 40; relative risk 2.3 [95% confidence interval, 1.3–4.1; P value < .05]).

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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References

1.Wisplinghoff, H, Bischoff, T, Tallent, SM, Seifert, H, Wenzel, RP, Edmond, MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004;39:309317.Google Scholar
2.Zickman, B. Perioperative microbiologic monitoring of tracheal aspirates as a predictor of pulmonary complications after cardiac operations. J Thorac Cardiovasc Surg 1996;111:12131218.Google Scholar
3.Murray, PR, Baron, EJ, Jorgensen, JH. Manual of Clinical Microbiology. 8th ed. Washington DC: American Society for Microbiology Press; 2003.Google Scholar
4.Garner, JS. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128140.Google Scholar
5.Miranda, G, Kelly, C, Solorzano, F, Leanos, B, Coria, R, Patterson, J E. Use of pulsed-field gel electrophoresis typing to study an outbreak of infection due to Serratia marcescens in a neonatal intensive care unit. J Clin Microbiol 1996;34:31383141.Google Scholar
6.Flynn, DM. Patients' endogenous flora as the source of “nosocomial” Enterobacter in cardiac surgery. J Infect Dis 1987;156:363368.CrossRefGoogle Scholar
7.Blot, S, Depuydt, P, Vandijck, D, Vandewoude, K, Peleman, R, Vogelaers, D. Predictive value of surveillance cultures and subsequent bacteremia with extended-spectrum β–lactamase-producing Enterobacteriaceae. Clin Infect Dis 2008;46:481482; author reply 482.Google Scholar