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Association between chlorhexidine gluconate concentrations and resistant bacterial bioburden on skin

Published online by Cambridge University Press:  11 October 2019

Gita Nadimpalli Open the ORCID record for Gita Nadimpalli [Opens in a new window] ,
Lyndsay M. O’Hara ,
Surbhi Leekha ,
David P. Calfee ,
Loren G. Miller ,
Lisa Pineles ,
Natalia Blanco Open the ORCID record for Natalia Blanco [Opens in a new window] ,
J. Kristie Johnson ,
Anthony D. Harris  and
for the CDC Prevention Epicenters Program
Gita Nadimpalli
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Lyndsay M. O’Hara
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Surbhi Leekha
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
David P. Calfee
Affiliation:
Division of Infectious Diseases, Weill Cornell Medicine, New York, New York
Loren G. Miller
Affiliation:
LA Biomedical Research Center at Harbor-UCLA Medical Center, Torrance, California
Lisa Pineles
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
Natalia Blanco
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
J. Kristie Johnson
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland
Anthony D. Harris*
Affiliation:
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland
*
Author for correspondence: Dr Anthony Harris, Email: [email protected]
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Abstract

We studied the association between chlorhexidine gluconate (CHG) concentration on skin and resistant bacterial bioburden. CHG was almost always detected on the skin, and detection of methicillin-resistant Staphylococcus aureus, carbapenem-resistant Enterobacteriaceae, and vancomycin-resistant Enterococcus on skin sites was infrequent. However, we found no correlation between CHG concentration and bacterial bioburden.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 40 , Issue 12 , December 2019 , pp. 1430 - 1432
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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