The publication of Professor Dewey’s Gifford Lectures, under the title “The Quest for Certainty,” affords a new opportunity for a study of the main emphases in the work of our leading American philosopher, and also for the clarification of the relations of his thought to the fundamental postulates of religion. A large part of the book is given over to an analysis of the conditions under which knowledge is attained. This paper will attempt a statement and criticism of the more important parts of the argument.