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Selection at the alcohol dehydrogenase locus in Drosophila melanogaster imposed by environmental ethanol

Published online by Cambridge University Press:  14 April 2009

J. G. Oakeshott
J. G. Oakeshott
Affiliation:
Department of Genetics, University of Adelaide, Adelaide, South Australia 5001, Australia
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Summary

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This paper describes selective differences imposed by environmental ethanol on six genotypes at the alcohol dehydrogenase (Adh) locus in Drosophila melanogaster. Probit analyses were used to relate differences between the percentage survival of adults of different Adh genotypes to ethanol concentration. Regression analyses were used to relate differences between the pre-adult developmental times of different Adh genotypes to ethanol concentration. The directions of differences between some of the genotypes were found to differ in these two components of fitness. The differences in developmental time are linearly related to the differences in the in vitro alcohol dehydrogenase activity expressed by these genotypes. Percentage survival differences amongst adults are not linearly related to these differences in enzymic activity. The development of AdhF AdhF pre-adults is retarded the least on ethanol impregnated media but AdhFAdhS adults are most likely to survive on such media.

Type
Research Article
Information
Genetics Research , Volume 26 , Issue 3 , December 1975 , pp. 265 - 274
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Bijlsma-Meeles, E. & Van Delden, W. (1974). Intra- and interpopulation selection concerning the alcohol dehydrogenase locus in Drosophila melanogaster. Nature 247, 369–371.CrossRefGoogle ScholarPubMed
Briscoe, D. A., Robertson, A. & Malpica, J. (1975). Dominance at Adh locus in response of adult Drosophila melanogaster to environmental alcohol. Nature 255, 148–149.CrossRefGoogle ScholarPubMed
Day, T. H., Hillier, P. C. & Clarke, B. (1974). Properties of genetically polymorphic isozymes of alcohol dehydrogenase in Drosophila melanogaster. Biochemical Genetics 11, 141–153.CrossRefGoogle ScholarPubMed
Finney, D. J. (1947). Probit Analysis: a statistical treatment of the sigmoid response curve. Cambridge University Press.Google Scholar
Gibson, J. (1970). Enzyme flexibility in Drosophila melanogaster. Nature 227, 959–961.CrossRefGoogle ScholarPubMed
Grell, E. H., Jacobson, K. B. & Murphy, J. B. (1968). Alterations of genetic material for analysis of alcohol dehydrogenase isozymes of Drosophila melanogaster. Annals of the New York Academy of Sciences 151, 441–455.CrossRefGoogle ScholarPubMed
Morgan, P. (1975). Selection acting directly on an enzyme polymorphism. Heredity 34, 124–127.CrossRefGoogle Scholar