Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-26T13:15:52.406Z Has data issue: false hasContentIssue false
  • English
  • Français

The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12

Published online by Cambridge University Press:  14 April 2009

Elinor Meynell  and
Naomi Datta
Elinor Meynell
Affiliation:
M.R.C. Microbial Genetics Research Unit, Hammersmith Hospital, London, W.12
Naomi Datta
Affiliation:
Postgraduate Medical School, Ducane Road, London, W.12
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The genetic elements promoting conjugation associated with transmissible drug resistance are of two or more kinds. Experiments with phage specific for F+ bacteria have shown that one large class differs from F essentially only in the production of a cytoplasmic repressor which limits the synthesis of the specific F pilus, whether by the RTF itself or by F when this is present in the same cell.

Type
Short Papers
Information
Genetics Research , Volume 7 , Issue 1 , February 1966 , pp. 134 - 140
Copyright
Copyright © Cambridge University Press 1966

References

REFERENCES

Bradley, D. E. (1964). The structure of some bacteriophages associated with male strains of Escherichia coli. J. gen. Microbiol. 35, 471–482.CrossRefGoogle ScholarPubMed
Brinton, C. C., Gemski, P. & Carnahan, J. (1964). A new type of bacterial pilus genetically controlled by the fertility factor of E.coli K12 and its role in chromosome transfer. Proc. natn. Acad. Sci. U.S.A. 52, 776–783.CrossRefGoogle Scholar
Broda, P. M. A. (1966). Genet. Res. (in preparation).Google Scholar
Clowes, R. C. & Rowley, D. (1954). Some observations on linkage effects in genetic recombination in Escherichia coli K12. J. gen. Microbiol. 11, 250–260.CrossRefGoogle Scholar
Crawford, E. M. & Gesteland, R. F. (1964). The adsorption of bacteriophage R-17. Virology, 22, 165–167.CrossRefGoogle Scholar
Datta, N. (1962). Transmissible drug resistance in an epidemic strain of Salmonella typhimurium. J. Hyg., Camb. 60, 301–310.CrossRefGoogle Scholar
Datta, N. (1965). Infective inheritance of drug resistance in bacteria. The Times, Lond., Science Rev., Autumn 1965.Google Scholar
Davis, J. E., Strauss, J. H. Jnr, & Sinsheimer, R. L. (1961). Bacteriophage MS2: another RNA phage. Science, N.Y. 134, 1427.Google Scholar
Dettori, R., Maccacaro, G. A. & Piccinin, G. L. (1961). Sex-specific bacteriophages of Escherichia coli K12. G. Microbiol. 9, 141–150.Google Scholar
Dettori, R., Maccacaro, G. A. & Turri, M. (1963). Sex-specific bacteriophages of E. coli K12. IV. Host specificity, pattern of lysis and lethality of phageμ2. G. Microbiol. 11, 15–34.Google Scholar
Egawa, R. & Hirota, Y. (1962). Inhibition of fertility by multiple drug-resistance factor in Escherichia coli K12. Jap. J. Genet. 37, 66–69.CrossRefGoogle Scholar
Falkow, S., Citarella, R. V., Wohlhieter, J. A. & Watanabe, T. (1965). The molecular basis of R factors. Bact. Proc. p. 14 only.Google Scholar
Hayes, W. (1953 a). The mechanism of genetic recombination in Escherichia coli. Cold. spring Harb. Symp. quant. Biol. 18, 75–93.CrossRefGoogle ScholarPubMed
Hayes, W. (1953 b). Observations on a transmissible agent determining sexual differentiation in Bact. coli. J. gen. Microbiol. 8, 72–88.Google Scholar
Lederberg, J. (1947). Gene recombination and linked segregations in Escherichia coli. Genetics, 32, 505–525.CrossRefGoogle ScholarPubMed
Lederberg, E. M. & Lederberg, J. (1953). Genetic studies of lysogenicity in Escherichia coli. Genetics, 38, 51–64.CrossRefGoogle ScholarPubMed
Loeb, T. & Zinder, N. D. (1961). A bacteriophage containing RNA. Proc. natn. Acad. Sci. U.S.A. 47, 282–289.CrossRefGoogle ScholarPubMed
Maccacaro, G. A., Colombo, C. & Nardo, A. di (1959). Studi sulle fimbrie batteriche. I. Lo studio genetico delle fimbrie. G. Microbiol. 7, 1–80.Google Scholar
Meynell, E. & Datta, N. (1965). Functional homology of the sex-factor and Resistance Transfer Factors. Nature, Lond. 207, 884–885.CrossRefGoogle ScholarPubMed
Meynell, E. & Datta, N. (1966). The nature and incidence of conjugation factors in Escherichia coli. Genet. Res. 7, 141–148.CrossRefGoogle ScholarPubMed
Monk, M. & Clowes, R. C. (1964). The regulation of colicin synthesis and colicin factor transfer in Escherichia coli K12. J. gen. Microbiol. 36, 385–392.CrossRefGoogle ScholarPubMed
Ørskov, I. & Ørskov, F. (1960). An antigen termed f+ occurring in F+E. coli strains. Acta path. microbiol. Scand. 48, 37–41.CrossRefGoogle Scholar
Scott, D. W. (1965). Serological cross reactions among the RNA-containing coliphages. Virology, 26, 85–88.CrossRefGoogle ScholarPubMed
Stocker, B. A. D., Smith, S. M. & Ozeki, H. (1963). High infectivity of Salmonella typhimurium newly infected by the col I factor. J. gen. Microbiol. 30, 201–221.CrossRefGoogle Scholar
Tatum, E. L. & Lederberg, J. (1947). Gene recombination in the bacterium. J. Bact. 53, 673–684.CrossRefGoogle ScholarPubMed
Valentine, R. C. & Strand, M. (1965). Complexes of F-pili and RNA bacteriophage. Science, N.Y. 148, 511–513.CrossRefGoogle ScholarPubMed
Watanabe, T. (1963). Episome-mediated transfer of drug resistance in Enterobacteriaceae. VI. High-frequency resistance transfer system in Escherichia coli. J. Bact. 85, 788–794.CrossRefGoogle ScholarPubMed
Watanabe, T. & Fukasawa, T. (1962). Episome-mediated transfer of drug resistance in Enterobacteriaceae. IV. Interactions between Resistance Transfer Factor and F-factor in Escherichia coli K12. J. Bact. 83, 727–735.CrossRefGoogle Scholar
Watanabe, T., Nishida, H., Ogata, C., Arai, T. & Sato, S. (1964). Episome-mediated transfer of drug resistance in Enterobacteriaceae. VII. Two types of naturally occurring R factors. J. Bact. 88, 716–726.CrossRefGoogle ScholarPubMed
Zinder, N. D. (1965). RNA phages. A. Rev. Microbiol. 19, 455–472.CrossRefGoogle ScholarPubMed