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Quantitative predictions of random segregation models of the ciliate macronucleus

Published online by Cambridge University Press:  14 April 2009

John R. Preer Jr
John R. Preer Jr
Affiliation:
Department of Zoology, Indiana University, Bloomington, Indiana 47401, U.S.A.
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Summary

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Models of the macronucleus in Paramecium tetraurelia which assume known levels of ploidy and random segregation of subunits smaller than a haploid set at both fission and macronuclear regeneration (MR) are not consistent with the hypothesis that senescence is due to aneuploid imbalance. Either senescence has some other basis or there is a mechanism for regular distribution of subunits at MR. Random segregation models for fission and MR are consistent with most data on survival and heterozygote stability, but if the ploidy level is 860 they fail to account for the data of Nyberg (this volume). Since the ploidy level may be higher than 860, models of random segregation cannot be ruled out for Paramecium. Models of the macronucleus in hypotrichs which assume randomly segregating chromosome fragments are consistent with data on survival and on stability of heterozygous genotypes at fission.

Type
Research Article
Information
Genetics Research , Volume 27 , Issue 2 , April 1976 , pp. 227 - 238
Copyright
Copyright © Cambridge University Press 1976

References

Allen, S. & Gibson, I. (1972). Genome amplification and gene expression in the ciliate macronucleus. Biochemical Genetics 6, 293–313.CrossRefGoogle ScholarPubMed
Ammermann, D. (1971). Morphology and development of the macronuclei of the ciliates Stylonychia mytilus and Euplotes aediculatus. Chromosoma 33, 209–238.CrossRefGoogle ScholarPubMed
Ammermann, D., Steinbrück, G., von Berger, L. & Hennig, W. (1974). The development of the macronucleus in the ciliated protozoan Stylonychia mytilus. Chromosoma 45, 401–429.CrossRefGoogle ScholarPubMed
Behme, R. J. & Berger, J. D. (1970). The DNA content of Paramecium aurelia, stock 51. Journal of Protozoology 17 (Suppl.), 20.Google Scholar
Berger, J. D. (1973). Nuclear differentiation and nucleic acid synthesis in well-fed excon-jugants of Paramecium aurelia. Chromosoma 42, 247–268.CrossRefGoogle ScholarPubMed
Cleffmann, G. (1968). Regulierung der DNA-Menge in Makronucleus von Tetrahymena. Experimental Cell Research 50, 193–207.CrossRefGoogle ScholarPubMed
Dippell, R. V. (1954). A preliminary report on the chromosomal constitution of certain variety 4 races of Paramecium aurelia. Caryologia 6 (Supplement), 1109–1111.Google Scholar
Fauré-Fremiet, E. (1953). L'hypothèse de la sénescence et les cycles de réorganization nucléaire chez Ciliés. Revue Suisse de Zoologie 60, 426–428.Google Scholar
Heckmann, K. (1967). Age-dependent intraclonal conjugation in Euplotes crassus. Journal of Experimental Zoology 165, 269–278.CrossRefGoogle Scholar
Kimball, R. F. (1943). Mating types in the ciliate Protozoa. Quarterly Review of Biology 18, 30–45.CrossRefGoogle Scholar
Kimball, R. F. & Barka, T. (1959). Quantitative cytochemical studies on Paramecium aurelia. II. Feulgen microspectrophotometry of the macronucleus during exponential growth. Experimental Cell Research 17, 173–182.CrossRefGoogle ScholarPubMed
Kimball, R. F. & Voght-Köhne, L. (1961). Quantitative cytochemical studies on Paramecium aurelia. IV. The effect of limited food and starvation on the macronucleus. Experimental Cell Research 23, 479–487.CrossRefGoogle Scholar
Kimura, M. (1957). Some problems of stochastic processes in genetics. Annals of Mathematical Statistics 28, 882–901.CrossRefGoogle Scholar
Michaelis, P. (1955). Über Gesetzmässigkeiten der Plasmon-Umkombination und über eine Methode zur Trennung einer Plastiden-, Chondriosomen-, resp. Sphaerosomen-, (Mikrosomen)- und einer Zytoplasmavererbung. Cytologia 20, 315–338.CrossRefGoogle Scholar
Nobili, R. (1960). The effect of macronuclear regeneration on vitality in Paramecium aurelia, syngen 4. Journal of Protozoology 7 (Supplement), 15.Google Scholar
Nobili, R. (1961). Effetti della rigenerazione del macronucleo sulla vitalita’ di Paramecium aurelia, syngen 4. Atti Associazione Genetica Italiana 6, 75–86.Google Scholar
Orias, E. & Flacks, M. (1975). Macronuclear genetics of Tetrahymena. I. Random distribution of macronuclear gene copies in T. pyriformis, syngen 1. Genetics 79, 187–206.CrossRefGoogle Scholar
Preer, J. R. Jr (1948). A study of some properties of the cytoplasmic factor ‘kappa’ in P. aurelia, variety 2. Genetics 33, 349–404.CrossRefGoogle Scholar
Prescott, D. M., Murti, K. G. & Bostock, C. J. (1973). Genetic apparatus of Stylonychia sp. Nature 242, 576, 597–600.CrossRefGoogle ScholarPubMed
Raikov, I. B. (1969). The macronucleus of ciliates. In Research in Protozoology, vol. iii. (ed. Chen, T. T.), pp. 1–128. New York: Pergamon.Google Scholar
Schensted, I. V. (1958). Model of subnuclear segregation in the macronucleus of ciliates. American Naturalist 92, 161–170.CrossRefGoogle Scholar
Schwartz, V. & Meister, H. (1975 a). Die Extinktion der feulgengafärbten Makronucleusanlage von Paramecium bursaria in der DNS-armen Phase. Archiv für Protistenkunde 117, 60–64.Google Scholar
Schwartz, V. & Meister, H. (1975 b). Einige quantitative Daten zum Problem des Alterns bei Paramecium. Arch. Protistenk. 117, 85–109.Google Scholar
Soldo, A. T. & Godoy, G. A. (1972). The kinetic complexity of Paramecium macronuclear deoxyribonucleic acid. Journal of Protozoology 19, 673–678.CrossRefGoogle ScholarPubMed
Sonneborn, T. M. (1947). Recent advances in the genetics of Paramecium and Euplotes. Advances in Genetics 1, 263–358.CrossRefGoogle ScholarPubMed
Sonneborn, T. M. (1954). The relation of autogamy to senescence and rejuvenescence in Paramecium aurelia. Journal of Protozoology 1, 38–53.CrossRefGoogle Scholar
Sonneborn, T. M. (1975). Paramecium aurelia. In Handbook of Genetics, vol. 2 (ed. King, R. C.), pp. 469–594. New York: Plenum Press.Google Scholar
Sonneborn, T. M., Schneller, M. V. & Craig, M. F. (1956). The basis of variation in phenotype of gene-controlled traits in heterozygotes of Paramecium aurelia. Journal of Protozoology 3 (Suppl.), 8.Google Scholar
Smith-Sonneborn, J. (1971). Age correlated sensitivity to ultraviolet radiation in Paramecium. Radiation Research 46, 64–69.CrossRefGoogle ScholarPubMed
Wolfe, J. (1967). Structural aspects of amitosis: a light and electron microscope study of the isolated macronuclei of Paramecium aurelia and Tetrahymena pyriformis. Chromosoma 23, 59–79.CrossRefGoogle Scholar
Woodard, J., Gelber, B. & Swift, H. (1961). Nucleoprotein changes during the mitotic cycle in Paramecium aurelia. Experimental Cell Research 23, 258–264.CrossRefGoogle ScholarPubMed
Woodard, J., Woodard, M. & Gelber, B. (1964). Cytochemical studies of conjugation in Paramecium aurelia. Journal of Cell Biology 23, 125 A.Google Scholar